Integument and Mammary Glands

This volume is one of a set of concise, well-illustrated and authoritative studies of natural and experimental lesions of laboratory animals (rat, mouse and hamster) arranged by organ systems. The volume Integument and Mammary Glands includes not only neoplastic but also non-neoplastic lesions as well as the effects of toxins. It proposes a standard, international nomenclature that is particularly important for the documentation and evaluation of pathologic data produced in safety studies. Emphasis is also given to precise differential diagnostic criteria. Useful data on pathogenesis, etiology, biologic behavior, frequency in different strains and under varying laboratory conditions are given. The significance of each lesion is considered and comparisons are made with other species including man. References to the world literature have been selected to permit access to the critically important publications on each subject. This volume, as others in the Monographs on the Pathology of Laboratory Animals series, will contribute to improved world-wide communication among scientists, industries and governments on the safety of foods, drugs and chemicals subjected to tests in animals.