Frailty and Sarcopenia in Cirrhosis

Puneeta Tandon, MDUniversity of AlbertaDepartment of MedicineDivision of Gastroenterology and Liver UnitEdmonton, Alberta Canada Aldo J. Montano-Loza, MDUniversity of AlbertaDepartment of MedicineDivision of Gastroenterology and Liver UnitEdmonton, AlbertaCanada

Definition & Diagnosis of Sarcopenia in the Research and Clinical Settings.- The Definition and Diagnosis of Frailty in the Research and Clinical Settings.- Deciphering the Cirrhotic Patient's Present Status: The Overlap between Physical Frailty, Disability and Sarcopenia.- The Pathogenesis of Physical Frailty and Sarcopenia.- Prognostic Implications of Physical Frailty and Sarcopenia Pre and Post Transplantation.- Nutritional Therapy in the Management of Physical Frailty and Sarcopenia.- Exercise Training in Patients with Cirrhosis.- Sex, Age and Ethnicity Dependent Variation in Body Composition: Can There Be a Single Cut-off?.- Muscle Mass versus Muscle Strength and Performance: Is Muscle Mass Measurement Alone Enough?.- The Role of Changes in Subcutaneous and Visceral Adiposity, Sarcopenic Obesity and Myosteatosis/Muscle Quality in Cirrhosis:How to Diagnose It and Its Contribution to Prognosis.- Evidence for the Assessment of Physical Frailty and Sarcopenia in Hospitalized Patientsand the Role of Assessing Changes Over Time.- Frailty and Sarcopenia in the Selection of Candidates for Liver Transplantation.- Physical Frailty and Sarcopenia in End Stage Liver Disease: Do They Improve after Liver Transplantation?.- Measures of Sarcopenia: The Utility of Ultrasound, Bioelectrical Impedance Analysis, and Single-Slice Cross-Sectional Imaging.- Upcoming Pharmacological and Interventional Therapies for the Treatment of Physical Frailty and Sarcopenia.- Should Frailty Include Multidimensional and Dynamic Factors?.- Hepatic Encephalopathy, Sarcopenia and Frailty.- A Research Wish List to Understand, Diagnose and Manage Frailty and Sarcopenia.