International Manual of Oncology Practice

Ramon Andrade de Mello, MD, PhD University of Algarve, Portugal Ramon Andrade Bezerra de Mello received the MD degree at the Faculty of Medicine, Federal University of Ceará, Fortaleza, Ceará, Brazil, with MD recognition from University of Lisbon, Portugal, and holds the Certificate in Medical Oncology by passing the European examination of ESMO (European Society for Medical Oncology), Lugano, Switzerland. He completed specialization in medicine and molecular oncology and his PhD in Oncology (lung cancer) at the Faculty of Medicine, University of Porto, Portugal. He also completed a post-doctoral clinical research fellowship in lung cancer clinical trials at the Lung Unit, Royal Marsden NHS Foundation Trust, Chelsea, London, United Kingdom, supported by the ESMO. Currently, he works in the Department of Medical Oncology at the Portuguese Oncology Institute, Porto, Portugal, and he teaches at the Department of Medicine of the University of Porto and School of Medicine, University of Algarve, Faro, Portugal. He is medical director of Oncoclínica/Euroclinics, Porto, Portugal. Prof. de Mello performs both basic and clinical research on angiogenesis, palliative medicine, internal medicine, colorectal cancer and lung cancer; further, he has an active office working. He is editor of 2 books (Tamoxifen Concepts and Cancer: New Paradigms and Vimentin Concepts and Molecular Mechanisms, Nova Science, NY, USA, 2013), author of several scientific articles, chapters and comments on basic and clinical research. He presented more than 50 papers in congresses and conferences in several countries, such as United States, Sweden, Brazil, Portugal and Spain. Furthermore, he serves as editorial board of several reputed scientific journals, such as PLoS ONE, Rare tumors, Oncology Reviews and scientific reviewer of the British Journal of Cancer, Journal of Thoracic Oncology, Annals of Internal Medicine and The Lancet. He participates as expert reviewer of grant applications at the University of Coimbra, Portugal, National Science Centre, Kraków, Poland, and the British Lung Foundation, London, UK. Prof. de Mello is an active member of the ESMO Young Oncologist Committee and consultant at Pfizer gastric cancer advisory board. SHORT CV GIANNIS MOUNTZIOS MD, MSc, PhD Dr Giannis Mountzios was born in Larissa, Greece, in 1974. He obtained his medical degree (MD) from the Aristotle University of Thessaloniki in 1998 with a scholarship from the Greek Ministry of Education and graduated from the Hellenic Military Medical Academy the same year. He completed his residency in Internal Medicine at the Airforce General Hospital of Athens and in Medical Oncology at the University of Athens School of Medicine, "Alexandra" University Hospital (Pr. M.A. Dimopoulos). He then obtained a master (MSc) in translational and clinical research in Oncology from the Institut Gustave-Roussy and the University Paris XI (Paris-Sud), France, in 2007 (Pr. Jean-Charles Soria) and became board-specified in Medical Oncology in 2009. In 2010 he obtained his PhD in Medical Oncology from the University of Athens School of Medicine. He is currently working as a consultant Medical Oncologist at the University of Athens School of Medicine. Dr Mountzios has received fellowships from the American Society of Clinical Oncology (Young Investigator award), the European Society for Medical Oncology (Annual Fellowship for Translational Research in 2005, Annual Fellowship for Clinical Research in 2009) and the Hellenic Society for Medical Oncology (HESMO). He is currently the General Secretary of the board of directors of HESMO, former chair of the HESMO young medical oncologists committee and former member of the steering committee of the young medical oncologists of ESMO. SHORT CURRICULUM VITAE Álvaro Tavares Álvaro A. Tavares, born in 1964, obtained h

Preface.- Cancer screening and epidemiology.- Cancer stem cells.- Apoptosis.- Angiogenesis.- Genetic basis of metastasis.- Anti-cancer Drugs.- Immuno-oncology.- Health Econimics.- Small cell lung cancer.- Mesothelioma.- Thymus.- Breast.- Oesophageal.- Gastric.- Colon.- Rectal.- Anal Canal Cancer.- Small intestine.- Liver Cancer.- Pancreatic Cancer.- Ovarian.- Cervical.- Vagina.- Gestacional trophoblastic disease.- Prostate Cancer.- Renal Cell Carcinoma.- Urothelial Cancer.- Germ-Cell Tumors.- Penile Cancer.- Squamous Head and neck.- Thyroid cancer.- Parotid Gland Tumors.- Melanoma.- Soft Tissue Sarcomas.- Bone Sarcomas.- GIST.- NET.- Primary brain tumor.- Acute Lymphoblastic Leukemia.- Myelodisplastic Syndrome.- Metabolic disturbance/paraneoplasic syndromes.- Spinal medular compression.- Superior vena cava syndrome.- Febrile neutropenia.- Chemotherapy-Induced Nausea and Vomiting.- Asthenia.- Oncological pain.- Bone Metastases.- Brain metastasis.- Palliative care.- Index.