Exposure and Risk Assessment of Pesticide Use in Agriculture

Prof. Claudio Colosio, M.D., is an expert in the field of pesticide exposure and risk assessment in all phases covered by the book (from registration to the field use). Aristidis Tsatsakis is Director of the Department of Toxicology and Forensic Sciences of the Medical School at the University of Crete and the University Hospital of Heraklion. He has more than 1000 publications, including 700 in ISI journals and is extensively cited. He was EUROTOX President (2014–16) and still an Emeritus Professor for the Federal Institute of Hygiene and Toxicology in Moscow. He is Doctor Honoris Causa of the Mendeleev Moscow University, the Far East Federal University (FEFU), Vladivostok, and the Carol Davila in Bucharest. He is a Foreign Member of the National Academy of Sciences of Russia (FMRAS) and a Fellow of the Academy of Toxicological Sciences (FATS, United States). He is the creator, founder, and chief scientific officer of ToxPlus SA. He developed numerous biomarkers of exposure and of effects for the pesticide and chemical toxicology field, uncovering the mechanistic understanding of the mode of actions, adverse outcome pathways, and clinical affects. He is currently the Editor of Food Chemical Toxicology, Editor-in-Chief of Toxicology Reports, Guest Editor of four special issues in Toxicology Letters, Toxicology and Food and Chemical Toxicology journals, Guest Editor of the RIFM-Food and Chemical Toxicology issue, Associate Editor, and member of the Editorial Boards in several other ISI indexed journals. He has also been recognized as Highly Cited Researcher 2020 in the field of Pharmacology–Toxicology (Publons). Stefan Mandic-Rajcevic, M.D., Ph.D., is an expert in the field of pesticide exposure and risk assessment in all phases covered by the book (from registration to the field use). Athanasios Alegakis, Ph.D. is an expert in the field of pesticide exposure and risk assessment in all phases covered by the book (from registration to the field use).

Section I – Regulatory exposure and risk assessment 1. From regulation to risk assessment

2. Models used in the world 3. Improving the models for regulatory exposure and risk assessment 4. Limit values definition and practical use

Section II – Exposure and risk assessment in field studies 5. Introduction to pesticide exposure monitoring 6. Skin Exposure: Whole-body and patch approaches 7. Respiratory exposure monitoring 8. Biological monitoring 9. Imitations of exposure monitoring methods and the way forward 10. Examples of exposure 11. Influence of environmental parameters on real-life exposure studies

Section III – Exposure and risk assessment for epidemiological studies 12. Introduction to epidemiological studies on pesticide exposure and effects – surrogate measures 13. Task exposure matrices 14. Questionnaires and Ranking models

Section IV – Future advances in exposure and risk assessment 15. Exposure and risk profiles 16. The interpretation of biological monitoring data: definition of biological exposure limits. 17. New biological monitoring methods 18. Tracer substances 19. Issues on risk assessment 20. Mixtures 21. Greenhouses