Genetics and Neurology

Offering guidance to clinical geneticists and neurologists about the mode of inheritance and genetic counselling risks for neurological conditions, this text groups subjects together under such headings as the muscular dystrophies, phakomatoses, peripheral neuropathies, and dementias. The author incorporates the advances in molecular biology that have occurred in the past 7 years and the localization of genes for many neurological disorders. A new chapter on mitochondrial diseases is included, as well as new sections on the Xp21 muscular dystrphies, the chronic spinal muscular atrophies, amyloid neuropathies, Rett's syndrome, torsion dystonia, trichothiodystrophy, early onset Cockayne syndrome and prion protein diseases. New descriptions of unusual genetic mechanisms are provided and 18 new illustrations and a map of the chromosomal locations of some neurological diseases are given.