Molecular Parasitology -

Molecular Parasitology

Protozoan Parasites and their Molecules
Buch | Softcover
IX, 547 Seiten
2018 | 1. Softcover reprint of the original 1st ed. 2016
Springer Wien (Verlag)
978-3-7091-4879-2 (ISBN)
246,09 inkl. MwSt
This book surveys the state of knowledge on "the molecules" of parasites - genomes, proteomes, glycomes and more. Comprehensive data will help show which traits enable the parasite to live in the human host, which cause disease and which are likely drug targets.
In the past years, genome projects for numerous human parasites have been completed and now allow first in depth comparisons and evolutionary conclusions. The genomes of parasites reflect the coevolution with their host, metabolic capacities depending on their respective habitat in the host. Gut parasites usually have an anaerobic metabolism, while blood parasites have an aerobic metabolism, intracellular parasites escape the immune system, while extracellular parasites evade the immune system, usually by antigenic variation. Comprehensive genome data now being available allow us to address profound scientific questions, such as which traits enable the parasite to survive in the human host, which to cause disease and which can be used as drug targets. This book intends to give an overview of the state of knowledge on "the molecules" of protozoan parasites - on their genomes, proteomes, glycomes and lipidomes.

Julia Walochnik and Michael Duchêne are associate professors at the Institute of Specific Prophylaxis and Tropical Medicine in the Center for Pathophysiology, Infectiology and Immunology of the Medical University of Vienna. Julia Walochnik´s work is focused on the molecular biology of Acanthamoeba spp. and other protozoan parasites. Together with her group she has published more than 130 scientific publications, including book chapters and reviews. Michael Duchêne studies the biochemistry and molecular biology of Entamoeba histolytica. Further interests are allergens and antigenic structures of bacteria. Together with his students and collaborators, he has published more than 90 scientific publications plus several book chapters.  

The Molecules :- Genomics.- Proteomics.-Glycomics. The Parasites (and their Molecules): Giardia.-Trichomonas.- Trypanosoma.- Leishmania.- Toxoplasma.- Plasmodium.- Acanthamoeba.- Entamoeba. Hot Topics : Phylogeny and Evolution.- Host-Parasite Interactions.- Parasite-Vector Interactions.- From Molecule to Drug.- Vaccine Development.

Erscheint lt. Verlag 5.7.2018
Zusatzinfo IX, 547 p. 58 illus., 46 illus. in color.
Verlagsort Vienna
Sprache englisch
Maße 155 x 235 mm
Gewicht 1139 g
Themenwelt Medizin / Pharmazie Medizinische Fachgebiete Mikrobiologie / Infektologie / Reisemedizin
Naturwissenschaften Biologie Mikrobiologie / Immunologie
Schlagworte drug design • Host parasite co-evolution • Leishmania • Tropical medicine • Trypanosoma
ISBN-10 3-7091-4879-0 / 3709148790
ISBN-13 978-3-7091-4879-2 / 9783709148792
Zustand Neuware
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