Myasthenia Gravis and Related Disorders

Henry J. Kaminski, Linda L. Kusner (Herausgeber)

Buch | Hardcover

XIII, 353 Seiten

2018 | 3rd ed. 2018
Springer International Publishing (Verlag)
978-3-319-73584-9 (ISBN)

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The third edition of this important, gold standard title outlines a range of significant advances in the study and understanding of myasthenia gravis. The overarching goal of this new edition is identical to the first and second -- to provide the clinician and the scientist with a common resource for understanding the profound achievements in the clinical, translational, and basic sciences of neuromuscular transmission disorders. In addition to several new authors and an extensive update of all chapters, this third edition includes summaries of pre-clinical research standards for autoimmune MG, along with a broad summary of MG clinical trial performance. The now greater understanding of the clinical presentation of MuSK-related MG and identification of potential new autoantigens, including LRP-4, is discussed. The development of treatment guidelines by groups in Japan, the United Kingdom, Germany, and an international consortium is also outlined. Myasthenia Gravis and Related Disorders, Third Edition , is an invaluable resource for meeting the many and varied needs of clinicians who treat patients with myasthenia gravis.

Henry J. Kaminski, MD Meta A. Neumann Professor and Chair of Neurology The George Washington University Department of Neurology Washington, DC, USA Linda L. Kusner, PhD Associate Professor The George Washington University Department of Pharmacology and Physiology Washington, DC, USA

Chapter 1. Neuromuscular Junction Physiology and PathophysiologyChapter 2. Acetylcholine Receptor StructureChapter 3. Immunopathogenesis of Myasthenia GravisChapter 4. Animal Models of Myasthenia Gravis for Preclinical EvaluationChapter 5. Epidemiology and Genetics of Myasthenia GravisChapter 6. Clinical Presentations of Myasthenia GravisChapter 7. Ocular MyastheniaChapter 8. Thymoma-associated Myasthenia GravisChapter 9. Electrodiagnosis of Neuromuscular Junction DisordersChapter 10. Autoantibody Testing in the Diagnosis and Management of Autoimmune Disorders of Neuromuscular Transmission and Related DiseasesChapter 11. Treatment of Myasthenia GravisChapter 12. Neurocritical Care of Myasthenic CrisisChapter 13. Thymectomy for Non-thymomatous Myasthenia GravisChapter 14. Lambert-Eaton SyndromeChapter 15 Acquired NeuromyotoniaChapter 16. Congenital Myasthenic SyndromesChapter 17. Toxic Neuromuscular Transmission DisordersChapter 18. Predictors of Psychological Health in Myasthenia GravisChapter 19. Myasthenia Gravis: Classification and Outcome MeasurementsChapter 20. Emerging Therapeutics for Myasthenia GravisChapter 21. Clinical Trial Design for Myasthenia Gravis

Erscheinungsdatum	04.04.2018
Reihe/Serie	Current Clinical Neurology
Zusatzinfo	XIII, 353 p. 52 illus., 15 illus. in color.
Verlagsort	Cham
Sprache	englisch
Maße	178 x 254 mm
Gewicht	931 g
Themenwelt	Medizin / Pharmazie ► Medizinische Fachgebiete ► Neurologie
Schlagworte	myasthenic syndromes • Neurology • Neuromuscular transmission • Pulmonology • toxic neuromuscular transmission disorders
ISBN-10	3-319-73584-5 / 3319735845
ISBN-13	978-3-319-73584-9 / 9783319735849
Zustand	Neuware