Scott-Brown's Otorhinolaryngology and Head and Neck Surgery

Editors John C Watkinson MSc (Nuclear Medicine; London). MS (London). FRCS (General Surgery). FRCS(ENT). DLO. One-Time Honorary Senior Lecturer and Consultant ENT/Head and Neck and Thyroid Surgeon. Queen Elizabeth Hospital, University of Birmingham NHS Trust and the Royal Marsden and Brompton Hospitals, Fulham Road, Chelsea, London, UK. Currently Honorary Consultant ENT/Head and Neck and Thyroid Surgeon. Great Ormond Street Hospital (GOSH) and St Georges Hospital NHS Trust, Tooting, London. Honorary Senior Anatomy Demonstrator, University College London (UCL). Business Director, Endocrine MDT. The Bupa Cromwell Hospital, Kensington, London. Raymond W Clarke BA, BSc, DCH, FRCS, FRCS(ORL) Consultant Paediatric Otolaryngologist, Royal Liverpool Children’s Hospital, Liverpool UK, Senior Lecturer and Associate Dean, University of Liverpool, UK Section Editors Louise Jayne Clark MB ChB, MD (dist), FRCS (ORL), FRCS (ENT). Queen Elizabeth University Hospital, Glasgow UK Adam J Donne, FRCS, Consultant Paediatric ENT Surgeon, Alder Hey, Liverpool, UK R. James A. England Consultant Otolaryngologist Head and Neck Surgeon, Honorary Senior Lecturer Hull and East Yorkshire NHS Hospitals Trust & Hull University, UK Prof Hisham M Mehanna PhD, BMedSc (hons), MBChB (hons), FRCS, FRCS (ORL-HNS) Chair of Head and Neck Surgery and Director of the Institute of Head and Neck Studies and Education, at the School Cancer Sciences, University of Birmingham, UK Gerald William McGarry MB.ChB. MD. FRCSEd. FRCS(ORL-HNS) FFSTEd Consultant Surgeon Head and Neck and Anterior Skull Base Surgery. Glasgow Royal infirmary, Greater Glasgow and Clyde NHS Hon.Clinical Senior Lecturer, University of Glasgow Sean Carrie, FRCS, Consultant Otolaryngologist / Skull base Surgeon, Newcastle upon Tyne Hospitals NHS Foundation Trust and Hon Senior Clinical Lecturer, Newcastle University, UK

Volume 1. Basic Science. CELL BIOLOGY. Molecular Biology . Genetics in Otology and Neurotology. Gene Therapy. Mechanisms of Anticancer Drugs. Radiotherapy. Apoptosis and Cell Death. Stem Cells. Aetiology and Pathogenesis of Goitre. Genetics of Endocrine. WOUND HEALING. Soft and Hard Tissue Repair. Skin Flap Physiology. Biomaterials, Tissue Engineering and their Application. IMMUNOLOGY. Defence Mechanisms. Allergy: Basic Mechanisms and Tests. Evaluation of the Immune System. Evaluation of the Immune System. HPV Molecular Biology. Rheumatological Diseases. MICROBIOLOGY. Microorganisms. Viruses and Antiviral Agents. Fungal Infections. Antimicrobial Therapy. HIV and Otolaryngology. HAEMATOLOGY. Blood Groups, Blood Components and Alternatives to Blood Transfusion. Haemato-Oncology. Haemostasis: Normal Physiology, Disorders of Haemostasis and Thrombosis. PHARMACOTHERAPEUTICS. Drug Therapy in Otology. Drug Therapy in Rhinology. Drug Therapy in Laryngology and Head and Neck Surgery. PERIOPERATIVE MANAGEMENT. Preparation of the Patient for Surgery. Recognition and Management of the Difficult Airway. Adult Anaesthesia. Adult Critical Care. Paediatric Intensive Care. SAFE AND EFFECTIVE PRACTICE. Training and Accreditation and Maintenance of Skills. Communication and the Medical Consultation. Clinical Governance Improving the Quality of Patient Care. Medical Ethics. Medical Jurisprudence in Otorhinolaryngology. Non-Technical Skills for Surgeons. INTERPRETATION AND MANAGEMENT OF DATA. Epidemiology. Outcomes Research. Evidence-Based Medicine. Critical Appraisal Skills. RECENT ADVANCES IN TECHNOLOGY. Electrophysiology and Monitoring. Optical Coherence Tomography. Positron Emission Tomography and Integrated PET/CT. Image Guided Surgery, 3D Planning and Reconstruction. Interventional techniques. Laser Principles in Otolaryngology, Head and Neck Surgery. Contact Endoscopy. Endocrine Surgery. OVERVIEW. History of Thyroid and Parathyroid Surgery. Developmental Anatomy of the Thyroid and Parathyroid Glands. Developmental Anatomy of the Pituitary Gland. Physiology of the Thyroid and Parathyroid Glands. Physiology of the Pituitary Gland. Imaging in Head and Neck Endocrine Disease. Thyroid Cytology and Histopathology of Head and Neck Endocrine Disease. THYROID DISEASE. Clinical Evaluation of the Thyroid Patient. Investigation of Thyroid Disease. Benign Thyroid Disease. Management of Differentiated Thyroid Cancer. Management of Medullary Thyroid Cancer. Management of Anaplastic Thyroid Cancer/Lymphoma. Management of Recurrent and Metastatic Disease. Adjuvant Treatments in Thyroid Cancer. THYROID SURGERY. Thyroidectomy. Surgery for Locally Advanced and Nodal Disease. Minimally Invasive and Robotic Thyroid Surgery. Management of the Enlarged Thyroid. PARATHYROID DISEASE. Clinical Evaluation of Hypercalcaemia. Investigation of Hyperparathyroidism. Management of Hyperparathyroidism. Management of Persistent and Recurrent Hyperparathyroidism. Management of Parathyroid Cancer. Bilateral Neck Exploration. PARATHYROID SURGERY. Minimally Invasive Parathyroidectomy. Surgical Failure and Reoperative Surgery. THYROID AND PARATHYROID OUTCOMES. Complications of Thyroid/Parathyroid Surgery and how to avoid them. Thyroid and Parathyroid Surgery: Audit and Outcomes. Medicolegal Aspects of Head and Neck Endocrine Surgery. PITUITARY DISEASE. Clinical Evaluation of the Pituitary Patient. Investigation of Pituitary Disease. Primary Pituitary Disease. Recurrent Pituitary Disease. Adjuvant Treatment of Pituitary Disease. Rhinology. Anatomy of Nose, Paranasal Sinuses and Skull Base. Outpatient Assessment. Physiology of the Nose and Paranasal Sinuses. Measurement of the Nasal Airway. Allergic Rhinitis. Non Allergic Rhinitis. Occupational Rhinitis. Rhinosinusitis. Nasal Polyposis. Fungal Rhinosinusitis. Medical Management of Rhinosinusitis. Surgical Management of Rhinosinusitis. The Frontal Sinus. Mucocoeles. Complications of Rhinosinusitis. Relationship of Upper and Lower Respiratory Tract. Nasal Septum and Nasal Valve. Nasal Septal Perforation. The Management of the Enlarged Turbinate. Epistaxis. Nasal and Facial Fractures. CSF Rhinorrhoea. Granulomatous Conditions of the Nose. Olfaction. Disorders of the Orbit. Diagnosis and Management of Facial Pain. Juvenile Angiofibroma. Endoscopic Management of Sinonasal Tumours. Management of Pituitary and Parasellar Diseases. Extended Anterior Skull Base Approaches. Radiolological Imaging in Rhinology and Skull Base Surgery.