Rare Tumors of the Thyroid Gland

Manuel Sobrinho-Simões MD, PhD, is co-founder and Director of IPATIMUP, Porto, Portugal. He is also Professor and Director of the Department of Pathology and Oncology of the Medical Faculty of the University of Porto, Portugal. His research interests are focused on thyroid cancer pathology: aetiopathogenesis,diagnosis, prognosis and therapy selection. He was President of the European Society of Pathology from 1999-2001 and is co-author of the 2nd, 3rd and 4th edition of the WHO book on endocrine tumours (1988, 2004 and 2016 (in preparation)). Manuel Sobrinho-Simões was voted the most influential pathologist in the World (2015) in a poll conducted by "The Pathologist". José Manuel Cameselle-Teijeiro, MD, PhD, is a member of the Department of Anatomic Pathology at the Clinical University Hospital in Santiago de Compostela, Spain, and is Associate Professor of the Medical School there. His research interests are focused on thyroid tumors pathology, with an emphasis on familial non-medullary thyroid cancer. He coordinates the Spanish Society of Anatomic Pathology`s Working Group on Endocrine Pathology and has co-authored several chapters of the 3rd and 4th editions of the WHO book on endocrine tumours.

Introduction.- Clinical Features.- Patient Examination.- Sampling Methods.- Rare variants of Papillary Carcinoma (PTCs).- Rare variants of Follicular Carcinoma (FTCs).- Rare variants of Hürthle cell (oncocytic) carcinoma.- Rare variants of Medullary carcinoma (MTCs).- Rare variants of poorly differentiated carcinoma.- Epithelial and border-line epithelial tumors.- Soft Tissue Tumors.- Lympho-hematopoietic Tumors.- Other Tumors.- Rare Benign Tumors and rare tumor-like conditions.- Therapeutic options.- Conclusions.- Diagram for differential diagnosis based on the predominant morphology.