Pathology of the Cervix

C Simon Herrington graduated in biochemistry with honours from the University of Cambridge in 1982 and medicine with honours from the University of London in 1985. He trained in Internal Medicine (MRCP 1988) and then became a CRC clinical research fellow in the Nuffield Department of Pathology, University of Oxford, receiving his DPhil in 1991. He was appointed clinical lecturer in pathology in Oxford where he completed his training in clinical cellular pathology (MRCPath 1994). He was appointed clinical senior lecturer in molecular pathology and consultant in pathology at the University of Liverpool in 1995 and was promoted to a Personal Chair in 1999. In 2003, he was appointed to the Chair of Pathology at the University of St Andrews, moving to the Chair of Pathology at the University of Dundee in 2010 and the Chair of Molecular Cancer Pathology at the University of Edinburgh in 2015. He also works as a consultant pathologist, specialising in gynecological pathology, was co-editor of the 4th Edition of the WHO Classification of Tumours of Female Reproductive Organs, and edited the 15th Edition of Muir’s Textbook of Pathology. He sits on the Board of the Association for International Cancer Research and is a past President of the International Society of Gynecological Pathologists. He is Editor in Chief of the Journal of Pathology and the Journal of Pathology: Clinical Research. He has a long-standing interest in the molecular pathology and optical imaging of cancer, collaborating with physical scientists to develop molecular imaging approaches to cancer diagnosis.

Development of the Uterine Cervix, and its Implications for the Pathogenesis of Cervical Cancer.- Human Papillomaviruses (HPVs).- Cervical screening: History, current algorithms and future directions.- Surgical and non-surgical management of cervical cancer: current practice and future directions.- Benign Lesions of the Cervix.- Cervical squamous intraepithelial lesions.- Squamous Cell Carcinoma of the Cervix.- Endocervical Adenocarcinoma in situ/Cervical Glandular Intraepithelial Neoplasia and Adenocarcinoma of the Usual Type.- Non-human papillomavirus (HPV)-related adenocarcinomas and their precursors.- Mesenchymal and Mixed Epithelial-Mesenchymal Neoplasms of the Cervix.- Other Cervical Neoplasms.- Appendix 1 Surgical cut up of cervical specimens.- Appendix 2 Dataset for reporting cervical neoplasia.- Appendix 3 TNM AND FIGO Staging of Cervical Carcinoma (ICD-O C53).- Appendix 4 Frozen section analysis in cervical carcinoma.