Prostaglandin E1

Prof.Dr.med. Curt Diehm, Chefarzt Innere Medizin am SRH-Klinikum Karlsbad-Langensteinbach; Herausgeber zahlreicher Patientenratgeber; Leitlinienautor; Vorsitzender der Deutschen Gefäßliga e.V..

Cellular Sites of Action of Prostaglandins in the Cardiovascular System.- On the Metabolism and Pharmacokinetics of Prostaglandin E1 Administered by Intra-arterial or Intravenous Infusions.- Actions of PGE1 PGE0 and 15-keto-PGE1 on Vessel Tone In Vitro.- 13,14-dihydro-PGE1 (PGE0) but not 15-keto-PGE1 is a Potent Inhibitor of Human Platelet and Neutrophil Activation.- Comparable Inhibitory Action of PGE1 and 13-14-dihydro-PGE1 on Smooth Muscle Cell Activity and Extracellular Matrix Production.- PGE1 and 13,14-dihydro-PGE1 Increase Low-Density Lipoprotein Receptors and Improve Arterial Wall Lipid Metabolism.- Effect of Intra-arterial and Intravenous Application of Prostaglandin E1 on Neutrophil Function in Peripheral Arterial Occlusive Disease.- A Comparison of Different Dosages of Intra-arterial and Intravenous Administered Prostaglandin E1 in Healthy Volunteers.- Transcutaneous Oxygen Pressure at Different Dosages of Intravenous Prostaglandin E1 in Patients with Severe Arterial Occlusive Disease: A Double-Blind, Placebo-Controlled Study.- Transcutaneous PO2 During Intra-arterial and Intravenous PGE1 Infusion in Patients with Critical Limb Ischaemia.- Effects of Intravenous PGE1 on Blood Flow and Microcirculation: A Double-Blind, Placebo-Controlled Study in Patients with Critical Limb Ischaemia.- Therapeutic Efficacy of Intravenous Prostaglandin E1 Versus Pentoxifylline in Patients with Intermittent Claudication.- Adjuvant Intravenous PGE1 Treatment After Profundaplasty for Limb Salvage.