Receptor Tyrosine Kinases

Analysis of Receptor Tyrosine Kinase (RTK) Phosphorylation by Immunoblotting.- Analysis of Changes in Phosphorylation of Receptor Tyrosine Kinases: Antibody Arrays.- Analysis of Epidermal Growth Factor Receptor Dimerization by BS3 Crosslinking.- Single-Molecule Optical Methods Analyzing Receptor Tyrosine Kinase Activation in Living Cells.- Evaluation of the Dimerization Profiles of HER Tyrosine Kinases by Time-Resolved Förster Resonance Energy Transfer (TR-FRET).- Applying the Proximity Ligation Assay (PLA) to Mouse Preimplantation Embryos for Identifying Protein-Protein Interactions In Situ.- Analysis of Receptor Tyrosine Kinase Gene Amplification on the Example of FGFR1.- Quantification of the Effects of Mutations on Receptor Tyrosine Kinase (RTK) Activation in Mammalian Cells.- Cell Surface Biotinylation of Receptor Tyrosine Kinases to Investigate Intracellular Trafficking.- Studying N-Linked Glycosylation of Receptor Tyrosine Kinases.- Identification of Receptor Protein Tyrosine Phosphatases (RPTPs) as Regulators of Receptor Tyrosine Kinases (RTKs) Using an RPTP siRNA-RTK Substrate Screen.- Downregulation of Receptor Tyrosine Kinases Through Ubiquitination: Analysis by Immunodetection.- Regulation of Receptor Tyrosine Kinases by miRNA: Overexpression of miRNA Using Lentiviral Inducible Expression Vectors.- Human Tumor Xenografts in Mouse as a Model for Evaluating Therapeutic Efficacy of Monoclonal Antibodies or Antibody-Drug Conjugate Targeting Receptor Tyrosine Kinases.- Receptor Tyrosine Kinase Targeting in Multicellular Spheroids.- Receptor Tyrosine Kinases and Drug Resistance: Development and Characterization of In Vitro Models of Resistance to RTK Inhibitors.