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Leucocyte Typing III

White Cell Differentiation Antigens

Andrew J. McMichael (Herausgeber)

Buch | Hardcover
1084 Seiten
1987
Oxford University Press (Verlag)
978-0-19-261552-7 (ISBN)
174,55 inkl. MwSt
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The third international workshop on leucocyte typing antigens brought together scientists from the major laboratories working in this field. In preparing for the workshop, more than 800 antibodies were exchanged, and this book contains the complete account of these experiments and analyses.
The third international workshop on leucocyte typing antigens brought together scientists from the major laboratories working in this complex and fast-moving field. In preparing for the workshop, more than 800 antibodies were exchanged. The results of these collaborative experiments were reported at the meeting, compared and summarized to produce a careful description of fifty human leucocyte antigens, twenty-four of them fully characterized for the first time. This book, contains the first and only complete account of these experiments and analyses. Antigens specific for or shared by T cells, activated lymphocytes, myeloid cells and platelets are featured. Details are given of their distribution, molecular structure and function. Much attention is given to the role that these antigens may play in investigating and understanding pathological processes, particularly in leukaemias and lymphomas. This workshop continues the collaboration established by A. Bernard and L. Boumsell, who organized the first workshop in 1980 (exchanging two hundred antibodies) bringing order and a standardized nomenclature to the field.
Readership: immunologists, cell biologists, molecular biologists, haematologists and pathologists.

C Milstein: Introductory remarks; Frances Gotch: Workshop structure and protocols; D J Spiegelhalter & W R Gilks: Statistical analysis; Bernadette Kienzle, Shirley Ellis, Winston Verbi, Michael Crumpton, Andrew McMichael, & Robert Knowles: Biochemical analysis of the Workshop antibodies with unknown specificities; Andrew J McMichael & Frances Gotch: T-cell antigens: new and previously defined clusters; Lewis L Lanier, An My Le, Athena H Ding, & Elizabeth L Evans: Analysis of the Workshop T-cell monoclonal antibodies by 'indirect two-colour immunofluorescence' and multiparameter flow cytometry; Soo Young Yang: Biochemical analysis of the Workshop antibodies of the T-cell antigen and activation antigen panels; T-cell antigens - papers; N R Ling, I C M MacLennan, & D Y Mason: B-cell antigens: new and previously defined clusters; B-cell antigens - papers; P C L Beverley: Activation antigens: new and previously defined clusters; Activation antigens - papers; Nancy Hogg & Michael A Horton: Myeloid antigens: new and previously defined clusters; Myeloid antigens - papers; Michael A Horton & Nancy Hogg: Platelet antigens: new and previously defined clusters; Platelet antigens - papers; Steve Cobbold, Geoff Hale, & Herman Waldmann: Non-lineage, LFA-1 family, and leucocyte common antigens: new and previously defined clusters; Non-lineage, LFA-1 family, and leucocyte common antigens - papers; Plenary papers; Nomenclature.

Reihe/Serie Oxford Medicine Publications
Zusatzinfo numerous halftone and line illustrations, bibliography
Verlagsort Oxford
Sprache englisch
Maße 190 x 250 mm
Gewicht 2461 g
Themenwelt Medizinische Fachgebiete Innere Medizin Hämatologie
Studium Querschnittsbereiche Infektiologie / Immunologie
ISBN-10 0-19-261552-1 / 0192615521
ISBN-13 978-0-19-261552-7 / 9780192615527
Zustand Neuware
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