Pediatric Hematology

Robert Wynn is Professor of Paediatric Haematology at the University of Manchester, and Consultant Paediatric Haematologist and Director of the Paediatric Blood and Marrow Transplant Programme at the Royal Manchester Children's Hospital. Rukhmi Bhat is Assistant Professor of Pediatrics at the Feinberg School of Medicine, Northwestern University, Illinois, and Attending Physician in Hematology/Oncology/Stem Cell Transplant at the Ann and Robert H. Lurie Children's Hospital, Chicago. Paul Monagle is Stevenson Professor and Head of the Department of Paediatrics at the University of Melbourne, and Former Director of the Department of Haematology at the Royal Children's Hospital, Melbourne.

1. Normal hemopoiesis and the physiology of blood; 2. The coagulation system; 3. Common laboratory tests used in hematology and how to interpret them; 4. Reference ranges in children; Clinical scenario 1. The child with newly presenting acute leukemia; 5. Neonatal anemia; 6. Neonatal abnormal myelopoiesis and the hematology of Down syndrome; 7. Neonatal thrombocytopenia; 8. Neonatal bleeding disorders; Clinical scenario 2. Hyperleucocytosis; 9. Neonatal thrombotic disorders; 10. Inherited bone marrow failure syndromes; 11. Acquired bone marrow failure syndromes: aplastic anemia; 12. Sideroblastic anemia; Clinical scenario 3. Management of the child with a mediastinal mass; 13. Iron deficiency; 14. Disorders of vitamin B12 and folate; 15. Hemolytic anemia; 16. Infections in hematology patients and the hematological features of infectious disease; Clinical scenario 4. The approach to the neutropenic child with fever; 17. Sickle cell disease; 18. Thalassemia; 19. Neutropenia; 20. Neutrophil function disorders; Clinical scenario 5. The approach to the child with pancytopenia; 21. Inherited thrombocytopenia; 22. Acquired thrombocytopenia and immune thrombocytopenia purpura (ITP); 23. Immune deficiency; 24. Hemophagocytic Lymphohistiocytosis (HLH) and other non-malignant histiocytic disorders; Clinical scenario 6. Does this child have lymphoma?; 25. Osteopetrosis; 26. Hemophilia; 27. Congential and acquired von Willebrand disease; 28. Rare inherited bleeding disorders; Clinical scenario 7. Diamond-Blackfan anemia, transient erythroblastopenia or other cause of red cell aplasia in children; 29. Acquired bleeding disorders; 30. Venous thrombosis in children; 31. Arterial thrombosis in children; 32. Stroke in children; Clinical scenario 8. Approach to evaluation for a bleeding disorder in a child with suspected non-accidental injury (NAI); 33. Anticoagulation in children; 34. Blood transfusion indications and safe use in children; 35. Adverse reactions to blood products and special transfusion circumstances; 36. Acute lymphoblastic leukemia; Clinical scenario 9. The neonate with catheter related thrombosis; 37. Acute myeloid leukemia; 38. Juvenile myelomonocytic leukemia (JMML) and myelodysplastic syndromes (MDS); 39. Principles of blood and marrow transplantation; Clinical scenario 10. Neonatal renal vein thrombosis.