Imaging in Dermatology

Michael R Hamblin Ph.D. is a Principal Investigator at the Wellman Center for Photomedicine at Massachusetts General Hospital, an Associate Professor of Dermatology at Harvard Medical School and is a member of the affiliated faculty of the Harvard-MIT Division of Health Science and Technology. He was trained as a synthetic organic chemist and received his PhD from Trent University in England. His research interests lie in the areas of photodynamic therapy (PDT) for infections, cancer, and heart disease and in low-level light therapy (LLLT) for wound healing, arthritis, traumatic brain injury and hair-regrowth. He directs a laboratory of around a sixteen post-doctoral fellows, visiting scientists and graduate students. His research program is supported by NIH, CDMRP, USAFOSR and CIMIT among other funding agencies. He has published 252 peer-reviewed articles, over 150 conference proceedings, book chapters and International abstracts and holds 8 patents. He is Associate Editor for 7 journals, on the editorial board of a further 12 journals and serves on NIH Study Sections. For the past 9 years Dr Hamblin has chaired an annual conference at SPIE Photonics West entitled "Mechanisms for low level light therapy" and he has edited the 9 proceedings volumes together with four other major textbooks on PDT and photomedicine. He has several other book projects in progress at various stages of completion. In 2011 Dr Hamblin was honored by election as a Fellow of SPIE. Pinar Avci, MD is a Research Fellow in Wellman Center for Photomedicine, Massachusetts General Hospital and Harvard Medical School Department of Dermatology, Boston USA. She received her MD degree in General Medicine from Semmelweis University, and is currently pursuing her PhD in Department of Dermatology, Venereology and Dermato-oncology, Semmelweis University, Budapest, Hungary. She is currently conducting research in the area of Photodynamic therapy (PDT) – a localized approach for treatment of cancer and infections and its effects in developing anti-tumor immunity. Gaurav Gupta did both his MBBS and MD at J.N. Medical College, Aligarh, India, and subsequently received PhD training at the Creighton University, Omaha, NE, USA and postdoctoral fellowship training at Massachusetts General Hospital, Harvard Medical School. Currently he is pursuing Residency training at Tufts Medical Center and a visiting postdoctoral fellow at Massachusetts General Hospital, Harvard Medical School.

1. Introduction
Michael R. Hamblin, Pinar Avci and Gaurav K. Gupta

2. The role of clinical photography in dermatology
Alexis Sidoroff

3. Dermoscopy
Aimilios Lallas, Zoe Apalla, Elizabeth Lazaridou, and Demetrios Ioannides

4. Trichoscopy: The dermatologist’s third eye
Uday Khopkar and Nilam Jain

5. Dermatoscopic correlates of nail apparatus disease
Sara Leite de Azevedo Campos and André Jacinto Garcez de Lencastre

6. Optical Coherence Tomography for Skin Cancer and Actinic Keratosis
Lotte Themstrup, and Gregor B.E. Jemec

7. Optical Coherence Tomography (OCT) Imaging of Skin Scarring and Fibrosis
Andrew Mamalis, Derek Ho and Jared Jagdeo

8. Polarization Speckles and Skin Applications
Tim K. Lee, Lioudmila Tchvialeva, Igor Markhvida, Haishan Zeng, Alexander Doronin, Igor Meglinski and David I. McLean

9. New Developments in Fluorescence Diagnostics
Juraj Hegyi and V. Hegyi

10. Ex vivo fluorescence microscopy: clinical applications in dermatology and surgical pathology
Caterina Longo, Stefano Gardini, Simonetta Piana, Fabio Castagnetti, Giuseppe Argenziano, Giovanni Pellacani and Moira Ragazzi

11. Coherent Raman Scattering Micros-copy in Dermatological Imaging
Hequn Wang and Conor L. Evans

12. Rapid real-time Raman spectroscopy and imaging-guided confocal Raman spectroscopy for in vivo skin evaluation and diagnosis
Jianhua Zhao, Harvey Lui, David I. McLean and Haishan Zeng

13. Surface Enhanced Raman Spectroscopy for Intradermal Measurements
Keren Chen, Yihong Ong, Clement Yuen and Quan Liu

14. Broadband Coherent Anti-Stokes Raman Scattering
Charles H. Camp Jr.

15. In Vivo Reflectance Confocal Microscopy in Dermatology
Ivette Alarcon, Caterina Longo and Salvador González

16. Hyperspectral and Multispectral Imaging in Dermatology
Fartash Vasefi, Nicholas MacKinnon and Daniel L. Farkas

17. Diffuse Reflectance Spectroscopy and Imaging
Austin J. Moy and James W. Tunnell

18. Spectral Imaging in Dermatology
Derek Ho, Ekaterina Kraeva, Jared Jagdeo, and Richard M Levenson

19. Applications of Multi-Photon Microscopy in Dermatology
Peter T. C. So, Elijah Yew and Christopher Rowlands

20. Non-linear microscopy in clinical dermatology
Riccardo Cicchi, Dimitrios Kapsokalyvas, and Francesco Saverio Pavone

21. Non-invasive topical in vivo imaging of skin: confocal reflectance microscopy and polarized light imaging
Steven L. Jacques

22. Polarization Optical Imaging of Skin Pathology and Ageing
Anna N. Yaroslavsky, Xin Feng and Victor A. Neel

23. Mechanical characterization of skin using surface acoustic waves
Chunhui Li, Guangying Guan, Ruikang Wang and Zhihong Huang

24. Photoacoustic tomography in the Diagnosis of Melanoma
Yong Zhou and Lihong V. Wang

25. Ultrasound Imaging in Dermatology
Ximena Wortsman

26. Optoacoustic Imaging of Skin
Mathias Schwarz, Juan Aguirre, Murad Omar and Vasilis Ntziachristos

27. Use of Total Body Photograph and Serial Digital Dermoscopy in Dermatology
Brian W. Petersen and H. William Higgins II

28. Functional MRI Advances to Reveal the Hidden Networks behind the Cerebral Processing of Itch
Alexandru D. P. Papoiu

29. Magnetic Resonance Microscopy of Skin
Katharina Eva Göbel
30. The Role of Magnetic Resonance Imaging in the Management of Anogenital Hidradenitis Suppurativa
Olwen Westerland, Geoff Charles-Edwards, Vicky Goh and Nyreen Griffin

31. Thermal imaging in dermatology, a review of current technologies and applications
Mathias Bonmarin and Frédérique-Anne Le Gal

32. The Role of PET/CT in Cutaneous Melanoma
Austin C. Bourgeois, Alexander S Pasiak and Yong C. Bradley

33. Molecular imaging of Merkel Cell Carcinoma
Volkan Beylergil, Julio Arevalo Perez, Joseph R. Osborne

34. Imaging in Merkel cell carcinoma
Lorenz Kadletz, Stefan F. Nemec, and Bobam M. Erovic

35. Images of Cutaneous Lymphoma
Alavi Abass, Tom Werner, Sara Fardin and Saeid Gholami

36. Imaging Cutaneous Squamous Cell Carcinoma of the Head and Neck
Geoffrey C. Casazza and Marcus M. Monroe

37. Imaging patterns of metastatic melanoma
Benjamin Peters and Filip M. Vanhoenacker

38. From Image to Information:  Image Processing in Dermatology and Cutaneous Biology
Marty O. Visscher, Shoná A. Burkes, R. Randall Wickett, Kenneth P. Eaton