Amyloid and Related Disorders (eBook)

Maria M. Picken, MD, PhDProfessor of PathologyDirector of Surgical PathologyPast President Renal Pathology SocietyLoyola University Medical CenterDepartment of Pathology2160 South First Avenue, Building 110, Room 2242Maywood, ILUSAGuillermo A. Herrera, M.D.Albert G. And Harriet G. Smith Professor and ChairLSU Health ShreveportDepartment of Pathology1501 Kings HighwayShreveport, LA  USAAhmet Dogan, MD, PhDChief, Hematopathology ServiceMemorial Sloan Kettering Cancer CenterDepartment of Pathology and Laboratory Medicine1275 York AvenueNew York, NY  USA

Part I - Introduction/GeneralChapter 1:  Aspects of the History and Nomenclature of Amyloid and AmyloidosisPer WestermarkChapter 2: Amyloid diseases at the molecular level: general overview and focus on AL amyloidosisMario Nuvolone, MD, PhD; Giovanni Palladini, MD, PhD; Giampaolo Merlini, MDChapter 3: AA AmyloidosisAmanda K. Ombrello, MD;  Ivona Aksentijevich, MDChapter 4: Leukocyte cell-derived chemotaxin 2 Amyloidosis (ALECT2)Oana Madalina Mereuta, MD PhD; Chris P. Larsen, MD; Ahmet Dogan, MD PhDChapter 5: The Hereditary AmyloidosesMerrill D. Benson, MDChapter 6: Dialysis-Associated AmyloidosisPaweena Susantitaphong, MD;  Laura M. Dember, MD;  Bertrand L. Jaber, MD, MSChapter 7: Localized amyloidoses and amyloidoses associated with aging outside the central nervous systemPer WestermarkChapter 8: Amyloid Deposition in the Central Nervous SystemFausto J. Rodriguez, Maria M. Picken, John M. Lee Part II - Non-Amyloid Protein DepositsChapter 9: Differential Diagnosis of Amyloid in Surgical Pathology: Organized Deposits and Other Materials in the Differential Diagnosis of AmyloidosisGuillermo A. Herrera and Elba A. Turbat-HerreraChapter 10: Light/Heavy Chain Deposition Disease as a Systemic DisorderGuillermo A. Herrera and Elba A. Turbat-HerreraChapter 11: Non-Randall Glomerulonephritis with Non-organized Monoclonal Ig DepositsPierre Ronco, Alexandre Karras, and Emmanuelle PlaisierChapter 12: Pathologies of renal and systemic intracellular paraprotein storage: crystalopathies and beyondMaria M. Picken and Ahmet DoganPart III - DiagnosisChapter 13: Diagnosis of Amyloid Using Congo RedAlexander J. HowieChapter 14: Diagnosis of Minimal Amyloid Deposits by Congo Red Fluorescence and Amyloidtype-specific Immunohistochemistry: A ReviewReinhold P. Linke, MD, PhDChapter 15: Thioflavin T Stain: An Easier and More Sensitive Method for Amyloid DetectionMaria M. Picken and Guillermo A. HerreraChapter 16: Fat tissue analysis in the management of patients with systemic amyloidosisJohan Bijzet, Ingrid I. van Gameren, Bouke P.C. HazenbergChapter 17: Generic diagnosis of amyloid – a summary of current recommendations and the editor’s comments on Chaps. 13-16Maria M. Picken Chapter 18: Typing of Amyloid for Routine Use on Formalin-Fixed Paraffin Sections of 626 Patients by Applying Amyloidtype-Specific Immunohistochemistry: A ReviewReinhold P. Linke, MD, PhDChapter 19: Amyloid Typing: Experience from a Large Referral CentreJanet A. Gilbertson, Julian D. Gillmore and Philip N. HawkinsChapter 20: Options for amyloid typing in renal pathology – the advantages of frozen section immunofluorescence and a summary of general recommendations regarding immunohistochemistry methodsMaria M. PickenChapter 21: Amyloid typing in plastic embedded tissue by immune-gold-silver methodAnne Räisänen-Sokolowski and Tom Tornroth Chapter 22: The Role of Immuno-electron Microscopy in Amyloid Typing: The Experience of the Pavia Referral CenterLaura Verga, Patrizia Morbini, Giovanni Palladini, Laura Obici, Gian Luca Capello, Marco Paulli, and Giampaolo MerliniChapter 23: Classification of amyloidosis by mass spectrometry-based proteomicsAhmet Dogan, MD, PhDChapter 24: The Role of Differential Proteomics in Amyloid Typing: The Experience of the Pavia Referral CenterFrancesca Lavatelli, Francesca Brambilla, Andrea Di Fonzo, Giovanni Ferraro, Giovanni Palladini, Pierluigi Mauri and Giampaolo MerliniPart IV- Ancillary Studies of AmyloidosisChapter 25: Laboratory Support for Diagnosis of AmyloidosisDavid L Murray, M.D., Ph.D. and Jerry A. Katzmann, Ph.D.Chapter 26: Bone Marrow Biopsy and Its Utility in the Diagnosis of AL AmyloidosisJohn C. Lee, M.D., Lawreen H. Connors, Ph.D., Carl J. O’Hara, M.D.Chapter 27: Laboratory Methods for the Diagnosis of Hereditary AmyloidosesS. Michelle Shiller,  Ahmet Dogan, Kimiyo M. Raymond, and W. Edward Highsmith, Jr.Part V- Organ Involvement in AmyloidosesChapter 28: Amyloidoses of the Kidney, the Lower Urinary and Genital Tracts (male and female) and the BreastMaria M. Picken and Ahmet DoganChapter 29: Cardiac AmyloidosisCarmela D. Tan, M.D. and E. Rene Rodriguez, M.D.Chapter 30: Amyloidosis of the Gastrointestinal Tract and LiverOscar W. Cummings, M.D., Merrill Benson, M.D.Chapter 31: Peripheral Nerve AmyloidosisAdam J. Loavenbruck, JaNean K. Engelstad, Christopher J. KleinChapter 32: Amyloidosis of the Lymph Nodes and the SpleenFiliz Sen MD, Ahmet Dogan MD PhDChapter 33: Amyloidosis of the lungKaren L. Grogg MD, Oana Madalina Mereuta MD PhD, Ahmet Dogan MD PhDChapter 34: Cutaneous AmyloidosisOana Madalina Mereuta MD PhD, Ahmet Dogan MD PhDChapter 35: Iatrogenic pharmaceutical amyloidosis associated with insulin and enfuvirtide administrationAhmet Dogan MD PhD, Oana Madalina Mereuta MD PhDPart VI- Clinical Issues and TherapyChapter 36: Clinical and pathologic issues in patients with amyloidosis – summary and practical comments regarding diagnosis, therapy and solid organ transplantationMaria M. Picken and Kevin BartonChapter 37: Emerging Therapies for AmyloidosisMerrill D. Benson Chapter 38: Modern Therapies in AA AmyloidosisAmanda K. Ombrello, M.D.Chapter 39: Medicolegal Issues of AmyloidosisTimothy Craig Allen, M.D., J.D.Chapter 40: Amyloidosis from the Patient's PerspectiveMuriel Finkel