Prescribing Medicines for Children

Section 1: Basic Clinical PharmacologyGeneral Principles of Clinical PharmacologyDrug AbsorptionDrug Distribution - from neonate to adolescentDrug Metabolism - adaptation over ageDrug Excretion - liver and renal maturationPharmacokinetics - from neonate to adolescentPharmacodynamics - based on practical examplesPharmacogenetics and pharmacogenomicsPrescribing in Liver DiseasePrescribing in Renal DiseaseAdverse Drug Reactions - Types A-ESection 2: Medicines for ChildrenTherapeutic indexDrug discovery - animal and preclinical studiesFormulations for childrenUnderstanding clinical trialsPharmacovigilance and pharmacoepidemiologyEuropean paediatric regulationsUS pediatric regulationsThe role of the pharmaceutical industry in developing new medicines for childrenNeonatal drug developmentOptimal prescribing in the resource poor settingEvidence based prescribingImproving training in clinical prescribingSection 3: Specific Clinical Prescribing AreasGastrointestinal systemCardiovascular systemRespiratory systemCentral nervous systemInfections and vaccinesEndocrinologyRenal diseaseHaemato-oncology and immunodeficiencyMalnutritionMusculoskeletal diseaseEye and ENT diseaseDermatologySection 4: Developing Good PracticeImproving practical prescribingSetting priorities lists for researchGRIP and the new training initiativesHarmonising international prescribingAppendicesKey references, websites, bibliography and future readingUseful reference tables such as Surface Area and other prescribing aids