CRISPR-Cas Systems -

CRISPR-Cas Systems

RNA-mediated Adaptive Immunity in Bacteria and Archaea
Buch | Softcover
X, 302 Seiten
2015 | 2013
Springer Berlin (Verlag)
978-3-642-42929-3 (ISBN)
246,09 inkl. MwSt
This book surveys research on a wide range of newly identified CRISPR-Cas systems, which defend bacteria and archaea against viruses and plasmids. Includes structural and functional analyses offering new insight into their functions and possible applications.

CRISPR/Cas is a recently described defense system that protects bacteria and archaea against invasion by mobile genetic elements such as viruses and plasmids. A wide spectrum of distinct CRISPR/Cas systems has been identified in at least half of the available prokaryotic genomes. On-going structural and functional analyses have resulted in a far greater insight into the functions and possible applications of these systems, although many secrets remain to be discovered.

In this book, experts summarize the state of the art in this exciting field.

Discovery and seminal developments in the CRISPR field.- Occurrence, diversity of CRISPR-Cas systems and genotyping implications.- Evolution and classification of CRISPR-Cas systems and Cas protein families.- Regulation of CRISPR-based immune responses.- crRNA Biogenesis.- Distribution and mechanism of the Type I CRISPR/Cas Systems.- Type II - Streptococcus thermophilus.- Type III CRISPR-Cas Systems and the Roles CRISPR-Cas in Bacterial Virulence.- CRISPR-Cas Systems to Probe Ecological Diversity and Host-Viral Interactions.- Roles of CRISPR in regulation of physiological processes.- Applications of the versatile CRISPR-Cas systems.- CRISPRs in microbial community context.

Erscheint lt. Verlag 29.1.2015
Zusatzinfo X, 302 p.
Verlagsort Berlin
Sprache englisch
Maße 155 x 235 mm
Gewicht 480 g
Themenwelt Medizin / Pharmazie Medizinische Fachgebiete Mikrobiologie / Infektologie / Reisemedizin
Naturwissenschaften Biologie Genetik / Molekularbiologie
Naturwissenschaften Biologie Mikrobiologie / Immunologie
Schlagworte Acquired immunity • archaea • Bacterial Genome • CRISPR • Virus
ISBN-10 3-642-42929-7 / 3642429297
ISBN-13 978-3-642-42929-3 / 9783642429293
Zustand Neuware
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