The Biology of Disease

Part One: Introduction: 1. The Nature of Disease; 2. Principles of Epidemiology; Part Two: Host Responses to Injury: 3. Cell Injury and Death; 4. Inflammation; 5. The Immune System; Part Three: Infection: 6. General Principles of Infection; 7. Bacterial Infection; 8. Viral Infection; 9. Fungal Infection; 10. Parasitic Infection; 11. Case studies: 11. 1 Fever, vomiting and neck stiffness in a child; 11. 2 Shortness of breath and vaginal discharge; Part Four: Immunological Disorders: 12. Hypersensitivity; 13. Auto-immunity; 14. Immunodeficiency; 15. Case studies: 15. 1 Persistent coughing up of blood and ankle-swelling; 15. 2 Breathlessness in a young man; Part Five: Nutritional and Gastro-intestinal Disorders: 16. Nutritional Disorders; 17. Jaundice and Liver Disorders; 18. Gastro-intestinal Disorders; 19. Case studies: 19. 1 Diarrhoea and abdominal distension; 19. 2 Abdominal pain and diarrhoea; 19. 3 Recurrent epigastric pain with abnormal liver function tests; Part Six: Blood and Circulatory Disorders: 20. Anaemia; 21. Disorders of Haemostasis; 22. Atherosclerosis; 23. Hypertension; 24. Case studies: 24. 1 Chest pain radiating to the left arm; 24. 2 Protein in the urine and hypertension; 24. 3 Fever and leg ulcer; Part Seven: Genetic Disorders: 25. Inherited Single Gene Disorders; 26. Chromosome Abnormalities; 27. Case studies: 27. 1 Rectal bleeding with diarrhoea; 27. 2 Heart Murmur and cleft palate; Part Eight: Neoplasia: 28. Principles of Neoplasia; 29. Oncogenes, Tumor Viruses and the Molecular Basis of Cancer; 30. Cancer: Invasion, Metastasis and Treatment; 31 Case studies: 31. 1 Easy Bruising, Weight loss and abdominal discomfort; 31. 2 Fever and cervical lymph node enlargement; 31. 3 Hoarseness and weight loss; Part Nine: Psychiatric Disorders: 32. Principles of Biological Psychiatry; 33. Biology of Mental Illness; 34. Case studies: 34. 1 Neurotic symptoms following a road traffic accident; 34. 2 Depressive illness in pregnancy; Index