Ovulation

1. An Overview of 37 Years of Research on Ovulation.- I. The Follicle.- 2. Histologic Definition of Ovarian Follicles and Analysis of Folliculogenesis Disruptions Due to Gene Mutations.- 3. The Graafian Follicle: A Functional Definition.- 4. The Critical Granulosa Cell Complement: Lessons from the Cyclin D2 Knockout.- 5. Ovarian Teratocarcinogenesis: A Consequence of Abnormal Regulation of Meiosis.- 6. The Role of the Oocyte in Ovulation.- II. The Gonadotropin Surge.- 7. The Physiology of the Human Midcycle Gonadotropin Surge.- 8. Duration, Amplitude, and Specificity of the Midcycle Gonadotropin Surge in Nonhuman Primates.- 9. The Many Faces of FSH.- III. The Intraovarian Steroid Microenvironment.- 10. Progesterone: Lessons from the Progesterone Receptor Knockout.- 11. Intraovarian Control of Ovulation: Lessons from Steroid Ablation/Replacement in Monkeys.- IV. Putative Periovulatory Intraovarian Regulators.- 12. The Ovarian Renin Angiotensin System Viewed Through Ovarian Perfusion.- 13. Ovarian Oxytocin: Periovulatory Production and Effects.- 14. Neurotrophins and the Ovulatory Process: A Role for NFG and trkA?.- 15. Cooperative Roles for the Angiopoietins and Vascular Endothelial Growth Factor in Ovarian Angiogenesis.- 16. Visualization of the Periovulatory Follicle: Morphological and Vascular Events.- 17. Inhibins, Activins, and Estrogens: Roles in the Ovulatory Sequence.- 18. Prostaglandins and Ovulation: From Indomethacin to PGHS-2 Knockout.- V. Putative Periovulatory Intraovarian Messengers/Facilitators.- 19. White Blood Cells: Active Participants in the Ovulatory Cascade.- 20. Ovarian Nitric Oxide: A Modulator of Ovulation and Oocyte Maturation.- 21. Oxidants and Antioxidants in Follicle/Oocyte Function.- 22. Periovulatory Changes in Ovarian Metalloproteinases and Tissue Inhibitors of Metalloproteinases (TIMPS) Following Indomethacin Treatment.- 23. Expression and Function of CCAAT/Enhancer Binding Proteins (C/EBPs) in the Ovary.- VI. Clinical Frontiers.- 24. Designer Gonadotropins and Receptors: The Prospect of Recombinant Technology.- 25. Triggering Ovulation with GnRH Analogs.- 26. Closing Comments: Ovulation from 1672 to 1998.- Author Index.