Chemotherapy

Advances in Cancer Chemotherapy.- Experimental Basis of Cancer Chemotherapy.- New Leads Towards Antitumor Selectivity in Therapeutics.- An Experimental Approach to Increase Selective Tumour Toxicity of Methotrexate.- Alterations in Intracellular Cyclic AMP as a Potential Form of Antitumour Chemotherapy.- The Drug-Carrier Potential of Liposomes in Cancer Chemotherapy.- Significance of Prostaglandins in Tumour Growth.- Oestrogen Binding as a Predictive Test for DMBA-Induced Tumour Response to Tamoxifen Therapy.- Action of Anticancer Drugs on the Cell Cycle. Chromosome Damage and Differential Stage Sensitivity.- Adriamycin Metabolism in Man.- Pharmacokinetics of Anticancer Drugs.- Pharmacokinetics and Metabolism of Anticancer Drugs.- The Activity of New Drugs Against Mouse Tumours.- Platinum Complexes as Anticancer Drugs.- Streptozotocin, Chlorozotocin, and Related Nitrosourea Antitumour Agents.- Analogues and Metabolites of Cyclophosphamide.- ICRF 159 and Other Bisdioxopiperazines.- Biological Basis of Radiosensitization by Hypoxic-Cell Radiosensitizers.- Bleomycin and Radiotherapy.- Experience with ICRF 159 and Radiotherapy in Combination in the Treatment of Soft Tissue Sarcomas.- Metronidazole (Flagyl) in Cancer Radiotherapy.- Possibilities of the Human Tumour/Nude Mouse System in Cancer Chemotherapy Research.- Chemotherapy of Transplantable Colon Tumours in Mice.- Utilization of Nitrosamine-Indueed Tumours as Models for Cancer Chemotherapy.- The Production of Osteolytic Substances by Human Breast Tumours.- The Biological Basis of Combination Chemotherapy.- Combination Chemotherapy of Advanced Gastrointestinal Carcinoma.- Combination Chemotherapy in Breast and Lung Cancer.- Chemotherapy of CNS Tumors.- Nitrosoureas: Clinical and Experimental Considerations in the Treatment of Brain Tumors.- Effect of CCNU on Survival, Objective Remissions, and Free Interval in Patients with Malignant Gliomas.- Intracavitary Glioma Chemotherapy.- Screening on Enzyme Inhibitors with Potential Antitumour Activity.- Recent Experience with Microbial Systems and Cancer Cells In Vitro in the Screening for Antitumor Antibiotics.- Problems Related to the Detection of Activity of Antitumour Antibiotics.- Attempts to Overcome Methotrexate Resistance: The Value of Drug Resistant Cell Lines.- In Vitro Mutagenesis by Anti-Cancer Drugs.- In Vitro Systems Using Micro-Organisms for Detection of Carcinogenic Agents.- In Vitro Screening of Cytotoxic Substances Using Different Tumour Cells.- In Vitro Methods for Use in Drug Metabolism Studies.- Some Problems in the Use of Short Term Cultures of Human Tumours for In Vitro Screening of Cytotoxic Drugs.- Combination of Corynebacterium parvum and Cytostatic Drugs in Disseminated Human Cancers.- Radiotherapy and Chemotherapy in Acute Leukaemia Related to Fatal Infection During Remission.- The Target Cell of Immunosuppressive Agents.- Immunological Aspects of Anticancer Drugs.- List of Contributors.