Advances in Pharmacology

Ferid Murad was born in Whiting, Indiana. Working concurrently on an M.D. and Ph.D. in Pharmacology, Dr. Murad graduated with both degrees from Case Western Reserve University, Cleveland, Ohio, in 1965. His many honors include the Alfred S. Maschke Award for Clinical Excellence from Case Western Reserve University in 1965. He has held several distinguished positions, including Acting Chairman in the Department of Medicine and Acting Division Chief, Division of Respiratory Medicine at Stanford University. He currently is CEO and President of Molecular Geriatrics Corporation in Lake Bluff, Illinois. Dr. Murad is married and has five children. Joseph T. Coyle, McLean Hospital, Harvard Medical School, Belmont, Massachusetts, USA

J. Hopkins, S. Siu, M. Cawley, and P. Rudd, Drug Therapy: The Impact of Managed Care.D. Spina, L.J. Landells, and C.P. Page, The Role of Phosphodiesterase Enzymes in Allergy and Asthma.D. Mochly-Rosen and L.M.Kauvar, Modulating Protein Kinase C Signal Transduction.M. Katori and M. Majima, Preventive Role of Renal Kallikrein-kinin System in the Early Phase of Hypertension and Development of New Anti-Hypertensive Drugs.M.D. Houslay, M. Sullivan, and G.B. Bolger, The Multi-Enzyme PDE4 Cyclic AMP Specific Phosphodiesterase Family: Intracellular Targeting, Regulation and Selective Inhibition by Compounds Exerting Anti-Inflammatory and Anti-Depressant Actions.A.H. Groll, S.C. Piscitelli, and T.J. Walsh, Clinical Pharmacology of Systemic Antifungal Agents: A Comprehensive Review of Agents in Clinical Use, Current Investigational Compounds and Putative Targets for Antifungal Drug Development.Subject Index.