The Physiological Basis of Veterinary Clinical Pharmacology (eBook)

The diversity of species in which drugs are used for clinical
purposes and the emphasis on various classes of drugs make
veterinary pharmacology a complex subject. Anatomical and
physiological features influence the pharmacokinetic behaviour of a
drug in a particular animal and the dosage required. This book is
concerned with the basis of species differences, the selection of
pharmacokinetic parameters and the interpretation of values
obtained. There are chapters on bioavailability and its application
to veterinary dosage forms, changes in drug disposition and
interspecies scaling, clinical selectivity and stereoisomerism,
drug permeation, antimicrobial disposition and specifics related to
neonatal animals.

The author has gathered all this information together in one
place so allowing the reader to make better selection of drug
preparations for animal dosages to effectively treat animal
diseases.

The book will prove valuable to clinical researchers in the
areas of pharmacology, anaesthesia, microbial infections and,
internal medicine as well as postgraduate students of these
disciplines.

The Author

J Desmond Baggot (MVM, PhD, DSc, FRCVS, DipECVPT) is currently
Visiting Professor of Veterinary Pharmacology at the School of
Veterinary Medicine, St George's University, Grenada, West Indies.
He was a contributing author and co-author of Antimicrobial
Therapy in Veterinary Medicine, 3rd Edition (2000) and
Development and Formulation of Veterinary Dosage Forms, 2nd
Edition (1998) and the author of Principles of Drug
Disposition in Domestic Animals (1977). Elucidations of the
processes that underline species variation in the disposition of
drugs and interpretation of the influence of disease states on drug
disposition have been the focus of his research endeavours. He was
a member of the Editorial Board of the Journal of Veterinary
Pharmacology and Therapeutics from 1978 to 1996. He is a former
Professor of Clinical Pharmacology at the School of Veterinary
Medicine, University of California, Davis and Preclinical
Veterinary Studies at the University of Zimbabwe, Harare.