Handbook of Forensic Drug Analysis (eBook)
584 Seiten
Elsevier Science (Verlag)
978-0-08-047289-8 (ISBN)
This complete volume is the only compendium of its kind on illicit drugs and analysis and should serve as a widely used reference for professionals. In addition, it can also be used as a standard textbook for graduate courses in forensic science.
- Contributed to by leading scientists from around the world.
- The only analysis book dedicated to illicit drugs of abuse
- Comprehensive coverage of sampling methods and various forms of analysis
The Handbook of Forensic Drug Analysis is a comprehensive chemical and analytic reference for the forensic analysis of illicit drugs. With chapters written by leading researchers in the field, the book provides in-depth, up-to-date methods and results of forensic drug analyses. This Handbook discusses various forms of the drug as well as the origin and nature of samples. It explains how to perform various tests, the use of best practices, and the analysis of results. Numerous forensic and chemical analytic techniques are covered including immunoassay, gas chromatography, and mass spectrometry. Topics range from the use of immunoassay technologies for drugs-of-abuse testing, to methods of forensic analysis for cannabis, hallucinogens, cocaine, opioids, and amphetamine. The book also looks at synthetic methods and law enforcement concerns regarding the manufacture of illicit drugs, with an emphasis on clandestine methamphetamine production. This Handbook should serve as a widely used reference for forensic scientists, toxicologists, pharmacologists, drug companies, and professionals working in toxicology testing labs, libraries, and poison control centers. It may also be used by chemists, physicians and those in legal and regulatory professions, and students of graduate courses in forensic science. - Contributed to by leading scientists from around the world- The only analysis book dedicated to illicit drugs of abuse- Comprehensive coverage of sampling methods and various forms of analysis
COVER 1
CONTENTS 5
FOREWORD 9
PREFACE 11
ABOUT THE AUTHORS 16
CHAPTER 1: OVERVIEW OF FORENSIC DRUG ANALYSIS 23
1.1 DRUG CLASSIFICATIONS 23
1.2 COLLECTION OF EVIDENCE IN DRUG CASES (DOCUMENTATION, SAFETY, PACKAGING, CUSTODY) 24
1.3 LABORATORY CAPABILITIES AND ACCREDITATION 26
DEFINITION OF TERMS 31
REFERENCE 34
CHAPTER 2: IMMUNOASSAY TECHNOLOGIES FOR DRUGS-OF-ABUSE TESTING 35
2.1 INTRODUCTION 35
2.2 RADIOIMMUNOASSAY (RIA) 39
2.3 ENZYME IMMUNOASSAY (EIA) 40
2.4 FLUORESCENCE POLARIZATION IMMUNOASSAY (FPIA) 46
2.5 KINETIC INTERACTION OF MICROPARTICLES IN SOLUTION (KIMS) 48
2.6 ONSITE (POINT-OF-COLLECTION) IMMUNOASSAYS 50
2.7. PERFORMANCE CHARACTERISTICS AND QUALITY MANAGEMENT OF IMMUNOASSAYS 53
2.8 SUMMARY 56
REFERENCES 56
CHAPTER 3: CANNABIS : METHODS OF FORENSIC ANALYSIS 65
3.1 QUALITATIVE SEIZED-DRUG ANALYSIS OF CANNABIS, HASH, AND HASH OIL: 66
3.2 PROFILING„PROVENANCE 86
3.3 IMMUNOASSAYS FOR THE DETECTION OF CANNABINOIDS IN BIOLOGICAL MATRICES 102
3.4 CONFIRMATION (CONFIRMATORY TEST) OF CANNABINOIDS IN URINE SPECIMENS 120
REFERENCES 152
CHAPTER 4: ANALYSIS OF THE HALLUCINOGENS 175
PART I: INFRARED (IR) SPECTROSCOPY 176
4.0 THEORETICAL BASIS 176
4.1 INFRARED SPECTROMETER INSTRUMENTATION 178
4.2 INFRARED SPECTROSCOPY OF LYSERGIC ACID DIETHYLAMIDE (LSD) 186
4.3 INFRARED SPECTROSCOPY OF PHENYLALKYLAMINES 187
4.4 INFRARED SPECTROSCOPY OF PHENCYCLIDINE AND ANALOGS 190
4.5 INFRARED SPECTROSCOPY OF TRYPTAMINES 192
4.6 FURTHER READING 194
PART II: MASS SPECTROMETRY 198
4.7 THEORETICAL BASIS 198
4.8 MASS SPECTROSCOPY OF LYSERGIC ACID DIETHYLAMIDE (LSD) 208
4.9 MASS SPECTROSCOPY OF PHENYLALKYLAMINES 209
4.10 MASS SPECTROSCOPY OF PHENCYCLIDINE AND ANALOGS 211
4.11 MASS SPECTROSCOPY OF TRYPTAMINES 213
4.12 FURTHER READING 217
ACKNOWLEDGMENT 224
REFERENCES 224
PART III: NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY 227
4.13 THEORETICAL BASIS 227
4.14 THE NMR EXPERIMENT 229
4.15 PHENCYCLIDINE AND RELATED SUBSTANCES 239
4.16 MDA AND ANALOGS 242
4.17 ERGOT AND OTHER INDOLE ALKALOIDS 249
4.18 TRYPTAMINES 251
REFERENCES 253
CHAPTER 5: COCAINE: METHODS OF FORENSIC ANALYSIS 257
5.1 INTRODUCTION 257
5.2 ORIGIN OF COCAINE SAMPLES 258
5.3 NONINSTRUMENTAL METHODS FOR DETECTION OF COCAINE 259
5.4 TRACE AND INSTRUMENTAL ANALYSIS 269
5.5 CONCLUSIONS 292
REFERENCES 292
CHAPTER 6: OPIOIDS: METHODS OF FORENSIC ANALYSIS 299
6.1 INTRODUCTION 299
6.2 PRELIMINARY METHODS FOR OPIATE DETECTION 300
6.3 ISOLATION OF OPIATES FROM BIOSAMPLES 306
6.4 PAPAVER SOMNIFERUM AS A SOURCE OF OPIATES 312
6.5 HEROIN AND ASSOCIATED ILLICIT OPIATE FORMULATIONS 318
6.6 OTHER OPIATE AGONISTS 343
6.7 SUMMARY 362
ABBREVIATIONS 364
REFERENCES 364
CHAPTER 7: AMPHETAMINES: METHODS OF FORENSIC ANALYSIS 379
7.1 INTRODUCTION 379
7.2 DETECTION 383
7.3 QUALITATIVE METHODS OF ANALYSIS 384
7.4 QUANTITATIVE METHODS OF ANALYSIS 396
7.5 COMPARATIVE ANALYSIS AND PROFILING 437
7.6 CONCLUSION 454
REFERENCES 455
CHAPTER 8: ILLICIT DRUG MANUFACTURE (WITH AN EMPHASIS ON CLANDESTINE METHAMPHETAMINE PRODUCTION): 475
8.1 RANGE OF OPERATIONS IN CLANDESTINE LABORATORIES 475
8.2 MANUFACTURE OF METHAMPHETAMINE 500
8.3 LAW ENFORCEMENT 536
8.4 CONCLUDING REMARKS 554
REFERENCES 554
INDEX 567
| Erscheint lt. Verlag | 31.12.2004 |
|---|---|
| Mitarbeit |
Herausgeber (Serie): Jay A. Siegel |
| Sprache | englisch |
| Themenwelt | Sachbuch/Ratgeber |
| Studium ► 2. Studienabschnitt (Klinik) ► Pharmakologie / Toxikologie | |
| Naturwissenschaften ► Chemie ► Analytische Chemie | |
| Recht / Steuern ► EU / Internationales Recht | |
| Recht / Steuern ► Strafrecht ► Kriminologie | |
| Sozialwissenschaften | |
| Technik | |
| ISBN-10 | 0-08-047289-3 / 0080472893 |
| ISBN-13 | 978-0-08-047289-8 / 9780080472898 |
| Haben Sie eine Frage zum Produkt? |
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