Leukemia and Lymphoma -

Leukemia and Lymphoma

Detection of Minimal Residual Disease
Buch | Softcover
257 Seiten
2010 | Softcover reprint of hardcover 1st ed. 2003
Humana Press Inc. (Verlag)
978-1-61737-279-7 (ISBN)
160,49 inkl. MwSt
In Leukemia and Lymphoma: Detection of Minimal Residual Disease, hands-on experts describe and discuss the minimal residual disease (MRD) methods they have successfully pioneered for leukemias and lymphomas. They apply reverse transcription PCR (RT-PCR) to acute myeloid leukemia (AML), chronic myelogenous leukemia (CML), and acute promyelocytic leukemia (APL). Other PCR methods are used for Non-Hodgkin's Lymphoma and for the monitoring of follicular lymphoma. Additional chapters address the use of real-time quantitative PCR (RQ-PCR), the emergent method of choice, in patients with acute lymphoblastic leukemia (ALL), the evaluation of MRD techniques in clinical trials, and the application of flow cytometry techniques.

1 Flow-Cytometry Methods for the Detection of Residual Leukemia.- 2 Flow-Cytometry—Based Studies of Minimal Residual Disease in Children with Acute Lymphoblastic Leukemia.- 3 PCR Methods for the Detection of Minimal Residual Disease in Childhood Acute Lymphoblastic Leukemia.- 4 Statistical Considerations in the Analysis of Minimal Residual Disease.- 5 The Application of Minimal Residual Disease Detection Methodology to the Clinical Decision-Making Process.- 6 Measurement of Minimal Residual Disease in Children Undergoing Allogeneic Stem Cell Transplant for Acute Lymphoblastic Leukemia.- 7 Molecular Investigation of Minimal Residual Disease in Adult Acute Lymphoblastic Leukemia of B Lineage.- 8 Investigation of Minimal Residual Disease in Acute Myeloid Leukemia by Immunophenotyping.- 9 Minimal Residual Disease in Acute Myeloid Leukemia: RT-PCR—Based Studies of Fusion Transcripts.- 10 Minimal Residual Disease in Acute Promyelocytic Leukemia.- 11 Minimal Residual Disease in Chronic Myelogenous Leukemia: Results of RT-PCR Detection of BCR-ABL Transcripts.- 12 Utility of PCR Assessment of Minimal Residual Disease After Stem Cell Transplantation in Non-Hodgkin’s Lymphoma.- 13 Real-Time Polymerase Chain Reaction of Genomic DNA for Quantitation of t(14;18).- 14 Monitoring Follicular Lymphoma by Polymerase Chain Reaction.- 15 Editors’ Notes.

Erscheint lt. Verlag 5.11.2010
Zusatzinfo 6 Illustrations, color; 21 Illustrations, black and white; XII, 257 p. 27 illus., 6 illus. in color.
Verlagsort Totowa, NJ
Sprache englisch
Maße 152 x 229 mm
Themenwelt Medizinische Fachgebiete Innere Medizin Hämatologie
ISBN-10 1-61737-279-X / 161737279X
ISBN-13 978-1-61737-279-7 / 9781617372797
Zustand Neuware
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