Handbook of Hematology Research -

Handbook of Hematology Research

Hemorheology, Hemophilia & Blood Coagulation
Buch | Hardcover
345 Seiten
2010
Nova Science Publishers Inc (Verlag)
978-1-60741-619-7 (ISBN)
319,95 inkl. MwSt
Haematology is the branch of medicine that deals with diseases of the blood and blood-forming organs. This book explores the immune responses and induction of immune tolerance to FVIII/FIX in haemophilia gene transfer, and the haemostatic changes in complicated pregnancy states like preeclampsia and pregnancy-induced hypertension.
Haematology is the branch of medicine that deals with diseases of the blood and blood-forming organs. Haemophilia is one of the most important diseases of haematology research. Medically, the classical treatment of haemophilia is transfusion therapy, which has been widely used for years. However, the transfusion can bring several complications for haemophilic patients, such as the onset of blood borne infectious diseases. This book discusses such diseases, as well as the new trend in blood product safety management. Until present, the new modality of gene therapy is the hope for successfully treating haemophilia. The authors of this book briefly review and discuss this new haemophilia treatment. In addition to examining the aetiology, pathogenesis and treatment of haemophilia, the factors involved in the activation of blood coagulation are examined as well. Other chapters in this book explore the immune responses and induction of immune tolerance to FVIII/FIX in haemophilia gene transfer, the haemostatic changes in complicated pregnancy states like preeclampsia and pregnancy-induced hypertension, a review of the new routine parameters for diagnosis of the early phases of pathologic disseminated intravascular coagulation (PDIC), and the quantitative and qualitative congenital plasminogen defects of the fibrinolytic system.

Preface; Congenital Defects of the Fibrinolytic System; New Methods for Studying Platelets and Red Blood Cells, Based Upon the Low-Angle Light Scattering Technique; Immune Tolerance Induction in Hemophilia Gene Therapy; Haemostatic Status in Normal and Complicated Pregnancies; Neutrophil Granulocytes in Hemostasis; Recent Developments in the Management of Hemophilia A with Inhibitors; Ambulatory Hemorheology Monitoring and its Impact on Healthcare Utilization in a Public Hospital; Arterial Hemodynamics and Pulse Wave Physiology; The Laboratory Diagnosis of the Pre-Phase of Pathologic Disseminated Intravascular Coagulation; Hemophilia Treatment: From Factor Transfusion to Gene Therapy; Hemophilia: Etiology, Pathogenesis and Treatment; Blood Borne Infections in Hemophilia; Effects of Exercise on Blood Coagulation Activity in Sickle Cell Trait Carriers: Abnormalities or Not?; Managing Acquired Hemophilia Viewed by Practical Cases; Disorders of the Haemostatic System in Patients with Solid Malignancies; Index.

Erscheint lt. Verlag 20.5.2010
Zusatzinfo Illustrations
Verlagsort New York
Sprache englisch
Maße 260 x 180 mm
Gewicht 834 g
Themenwelt Medizinische Fachgebiete Innere Medizin Hämatologie
ISBN-10 1-60741-619-0 / 1607416190
ISBN-13 978-1-60741-619-7 / 9781607416197
Zustand Neuware
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