Acute Myelogenous Leukemia

Lalitha Nagarajan is an Associate Professor, Department of Molecular Genetics, The University of Texas, M.D. Anderson Cancer Center, Houston, Texas.

The Leukemia Stem Cell.- Epigenetic Mechanisms in AML - a Target for Therapy.- Chromosomal Translocations in AML: Detection and Prognostic Significance.- Chromosomal Deletions in AML.- Genes Predictive of Outcome and Novel Molecular Classification Schemes in Adult Acute Myeloid Leukemia.- Receptor Tyrosine Kinase Alterations in AML -- Biology and Therapy.- Lineage Specific Transcription Factor Aberrations in AML.- Pro-leukemic RUNX1 and CBFss Mutations in the Pathogenesis of Acute Leukemia.- Acute Myeloid Leukemia with Mutated Nucleophosmin (NPM1): Molecular, Pathological and Clinical Features.- MicroRNAs: New Players in AML Pathogenesis.- Murine Models of Human Acute Myeloid Leukemia.- AML and Apoptosis.- Acute Promyelocytic Leukemia, a Paradigm for Differentitation Therapy.- Immunotherapy of AML.- Therapy of Acute Myelogenous Leukemia in Adults.