An Invitation to Biomathematics

Raina Robeva was born in Sofia, Bulgaria. She holds a PhD in Mathematics from the University of Virginia and has broad research interests spanning theoretical mathematics, applied probability, and systems biology. Robeva is the founding Chief Editor of the journal Frontiers in Systems Biology and the lead author/editor of the books An Invitation to Biomathematics (2008), Mathematical Concepts and Methods in Modern Biology: Using Modern Discrete Models (2013), and Algebraic and Discrete Mathematical Methods for Modern Biology (2015), all published by Academic Press. She is Professor of Mathematical Sciences and Director of the Center for Science and Technology in Society at Sweet Briar College. Dr. Boris Kovatchev is Professor at the University of Virginia School of Medicine and School of Engineering, and founding director of the Center for Diabetes Technology. He has a 30-year track record in mathematical modeling, biosimulation, and algorithm development. Currently, he is Principal Investigator of several projects dedicated to Diabetes Data Science and the development of artificial pancreas and decision support systems, including the large-scale NIH International Diabetes Closed-Loop Trial and the UVA Strategic Investment Fund project “Precision Individualized Medicine for Diabetes”. Dr. Kovatchev is author of over 200 peer-reviewed publications and holds 85 patents.

1. Processes that Change with Time: Introduction to Dynamical Systems / 2. Complex Dynamics Emerging from Interacting Dynamical Systems / 3. Mathematics in Genetics / 4. Quantitative Genetics and Statistics / 5. Risk Analysis of Blood Glucose Data / 6. Predicting Septicemia in Neonates / 7. Cooperative Binding: How Your Blood Transports Oxygen / 8. Ligand Binding, Data Fitting, and Least-Squares Estimates of Model Parameters / 9. Endocrinology and Hormone Pulsatility / 10. Endocrine Network Modeling: Feedback Loops and Hormone Oscillations / 11. Detecting Rhythms in Confounded Data / 12. Using Microarrays to Study Gene Expression Patterns