Digital Technologies in Movement Disorders

Dr. Sánchez Ferro specialized in neurology at the Hospital 12 de Octubre in Madrid (Spain). In the same center, he was trained specifically for the management of Parkinson's disease thanks to a program of the Carlos III Research Institute (Río Hortega Program). During this period, he visited prestigious centers such as the "Hertie Institut" in Tübingen (Germany) and the "MINDS laboratory" from Harvard University where he also received training in neurodegenerative diseases. In 2013, Dr. Sánchez Ferro received a scholarship from a program of the Community of Madrid and the Massachusetts Institute of Technology (Cambridge, USA) to be part of a biomedical innovation program. As part of it, he developed new methods for the objective quantification of Parkinson's disease signs. Currently, Dr. Sánchez-Ferro continues applying these skills in his position as neurologist and researcher at 12 de Octubre Hospital and Chief Medical Officer of Leuko Labs. He is also Director of the Clinical Outcomes Assessment Program at the International Parkinson and Movement Disorders Society (MDS) and is an active member of the Technology Study Group of the MDS Society. Dr Monje specialized in neurology at the Hospital Clínico San Carlos in Madrid (Spain). She received her PhD in Neuroscience from Universidad Autónoma de Madrid working in a progressive model of Parkinson’s disease in non-human primate. She posteriorly pursued a clinical and research fellowship in Movement in HM-CINAC, where she got experience in new technologies for the objective quantification of movement disorders. Currently, Dr. Monje works as postdoctoral scholar in Northwestern University, Chicago (USA). She is the co-Chair of the Electronic Clinical Outcomes Assessment Program at the International Parkinson and Movement Disorders Society (MDS).

Preface

Alvaro Sanchez Ferro and Mariana Hernandez Gonzalez-Monje

1. Applications of artificial intelligence in movement disorders, in the pursuit of personalized healthcare

Jorge Cancela, Ernst Bos, Jaclyn Loushine, Dario Motti and Foteini Orfaniotou

2. Machine learning basic concepts for the movement disorders specialist

Elina L. van den Brandhof, A.M. Madelein van der Stouwe, Jelle R. Dalenberg, Inge Tuitert, Marina A.J. Tijssen and Michael Biehl

3. Digital biomarkers in movement disorders

Daniele Urso, Daniel J van Wamelen, Dhaval Trivedi, K Ray Chaudhuri and Cristian Falup-Pecurariu

4. Basic concept of sensors for movement disorders specialists

Raquel Bouça-Machado, Linda Azevedo Kauppila, Tiago Guerreiro and Joaquim J Ferreira

5. Wearable systems in movement disorders

Edoardo Bianchini and Walter Maetzler

6. Digital gait and balance measures

Fay B. Horak, Vrutangkumar Shah and Martina Mancini

7. The challenges and opportunities for remotely evaluating movement disorders

Rochester Lynn, Del Din Silvia, Hu Michele T, Morgan Catherine and Carroll Camille

8. eCOA, ePROs and other digital health solutions in movement disorders

Sylvie Grosjean and Tiago A. Mestre

9. Telemedicine in movement disorders

Esther Cubo

10. Video and optoelectronics in movement disorders

Cristina Caro and Norberto Malpica

11. Therapeutic applications and technical developments of focused ultrasound for movement disorders

Jorge U. Máñez-Miró, Elena Natera-Villalba and Raúl Martínez-Fernández

Glossary

Alvaro Sanchez Ferro and Mariana Hernandez Gonzalez-Monje