Genomics in Biosecurity

Dr. Manousos E. Kambouris serves as a Scientific Advisor for the Golden Helix Foundation, Craven House, London, UK, an international non-profit research organization aiming to advance research and education in the area of genomic and personalized medicine and as a Post Doc Researcher in the Laboratory of Pharmacogenomics and Individualized Therapy, Department of Pharmacy, University of Patras. Dr. Kambouris has long participated in different aspects and applications of microbiology, human genomics, biosecurity and cancer research. In his own work, he pursues an integrative approach to microbiomics, employing various -omics-driven approaches and realizing their application in human health, selective and personalized medicine, and panbiosurveillance among other areas. He has published widely in such peer-reviewed journals as OMICS-JIB, Hemoglobin, Medical Mycology, FEMS Immunology & Medical Microbiology, Public Health Genomics, and Future Microbiology.

Part I. The Spontaneous Risk: Microbes and Bugs 1. Exploring the concepts: Biosecurity, biodefense and biovigilance 2. The concept of humanome and the microbiomic dimension 3. Global catastrophic biological risks: Nature and response 4. Surveillance policies, levels, patterns, and techniques 5. The emerging pathogens: Nature, status, and threat 6. Non-microbial biothreats: DNA, prions, and (bio)regulators/(bio)toxins 7. Public health microbiomics

Part II. The Perpetrated Biothreat: Bioterrorism, Biocrime, and Biowarfare 8. Bio-offense: Black biology 9. Bio-offense: Technical means, tactical approaches, operational orientations, and strategic concepts

Part III. Biodefense Response and Intervention 10. Biodefense response: Cognition and diagnosis 11. Bio-defence build 2.0: The muscle 12. The genomic dimension in biodefense: Therapeutics 13. The genomic dimension in biodefense: Decontamination 14. Regulation and legislation 15. Epilogue: Resilience and preparedness, the case study of the United States