Applied Computational Genomics
Seiten
2019
|
Softcover reprint of the original 2nd ed. 2018
Springer Verlag, Singapore
978-981-13-4561-6 (ISBN)
Springer Verlag, Singapore
978-981-13-4561-6 (ISBN)
The volume provides a review of statistical development and application in the area of human genomics, including candidate gene mapping, linkage analysis, population-based genome-wide association, exon sequencing, and whole genome sequencing analysis.
The volume provides a review of statistical development and application in the area of human genomics, including candidate gene mapping, linkage analysis, population-based genome-wide association, exon sequencing, and whole genome sequencing analysis. The authors are extremely experienced in the field of statistical genomics and will give a detailed introduction to the evolution of the field, as well as critical comments on the advantages and disadvantages of the proposed statistical models. The future directions of translational biology will also be described.
The volume provides a review of statistical development and application in the area of human genomics, including candidate gene mapping, linkage analysis, population-based genome-wide association, exon sequencing, and whole genome sequencing analysis. The authors are extremely experienced in the field of statistical genomics and will give a detailed introduction to the evolution of the field, as well as critical comments on the advantages and disadvantages of the proposed statistical models. The future directions of translational biology will also be described.
Dr. Yin Yao is investigator in the Intramural Research Program at the National Institute of Mental Health, Bethesda, Maryland USA.
Introduction.- Exploring Polygenic Overlap Between ADHD and OCD.- Concepts of Genetic Epidemiology.- Rare Variants Analysis in Unrelated Individuals.- Whole Genome Association of Treatment Response in OCD.- QTL Mapping of Molecular Traits for Studies of Human Complex Diseases.- From Family Study to Population Study: A History of Genetic Mapping for Nasopharyngeal Carcinoma (NPC).- Test for Nonlinear Dependence of Two Continuous Variables.- Analytical Approaches for Exome Sequence Data.- Machine Learning Approaches: Data Integration for Disease Prediction and Prognosis.- OCD Genomics and Future Looks.
| Erscheint lt. Verlag | 8.2.2019 |
|---|---|
| Reihe/Serie | Translational Bioinformatics ; 13 |
| Zusatzinfo | 13 Illustrations, color; 1 Illustrations, black and white; VII, 150 p. 14 illus., 13 illus. in color. |
| Verlagsort | Singapore |
| Sprache | englisch |
| Maße | 155 x 235 mm |
| Themenwelt | Mathematik / Informatik ► Informatik ► Theorie / Studium |
| Informatik ► Weitere Themen ► Bioinformatik | |
| Medizin / Pharmazie ► Medizinische Fachgebiete | |
| Studium ► 2. Studienabschnitt (Klinik) ► Humangenetik | |
| Naturwissenschaften ► Biologie ► Genetik / Molekularbiologie | |
| Technik ► Umwelttechnik / Biotechnologie | |
| Schlagworte | exon sequencing • Gene Mapping • linkage analysis • population-based genome-wide association • whole genome sequencing analysis |
| ISBN-10 | 981-13-4561-9 / 9811345619 |
| ISBN-13 | 978-981-13-4561-6 / 9789811345616 |
| Zustand | Neuware |
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