The Theoretical Foundations of Cancer Chemotherapy Introduced by Computer Models
Seiten
1992
Academic Press Inc
978-0-12-379030-9 (ISBN)
Academic Press Inc
978-0-12-379030-9 (ISBN)
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Describes the principles of cancer chemotherapy quantitatively, using computer modelling. The book includes a computer program on disk to allow the user to model tumour biology and drug effects. This allows a trial and error approach to understanding the principles of chemotherapy.
This book is intended for oncologists, pharmacologists, biochemists, biomathematicians, and cell biologists in academia as well as in industry; graduate, medical, and senior undergraduate students in the biological sciences. This is the first book to describe the principles of cancer chemotherapy quantitatively, using computer modelling. It includes a computer program on disk that allows the user to model tumour biology and drug effects. This ability to treat imaginary tumours with imaginary drugs and to change the properties of each makes it possible to use a trial and error approach to the understanding of the principles of chemotherapy.
This book is intended for oncologists, pharmacologists, biochemists, biomathematicians, and cell biologists in academia as well as in industry; graduate, medical, and senior undergraduate students in the biological sciences. This is the first book to describe the principles of cancer chemotherapy quantitatively, using computer modelling. It includes a computer program on disk that allows the user to model tumour biology and drug effects. This ability to treat imaginary tumours with imaginary drugs and to change the properties of each makes it possible to use a trial and error approach to the understanding of the principles of chemotherapy.
Introduction - models as tools for teaching and research; cell cycle effects of drugs; anticancer drug selectivity; quiescent cells, differentiated cells and lost cells; pharmacokinetic models; invasion and metastasis; the blood-brain barrier; cancer treatment and the immune response; drug resistance and its implications for treatment strategy; the growth kinetics of large tumours; the biochemical basis of anticancer drug selectivity; biochemical principles of drug interaction; cytokinetics, pharmacokinetics, and inhibition kinetics - a unified model. Appendices: chemical structures of the anticancer drugs studied by the models; notes on the programming.
| Zusatzinfo | bibliography, index |
|---|---|
| Verlagsort | San Diego |
| Sprache | englisch |
| Gewicht | 805 g |
| Themenwelt | Informatik ► Grafik / Design ► Digitale Bildverarbeitung |
| Medizin / Pharmazie ► Medizinische Fachgebiete | |
| Studium ► Querschnittsbereiche ► Infektiologie / Immunologie | |
| Naturwissenschaften ► Biologie ► Biochemie | |
| ISBN-10 | 0-12-379030-1 / 0123790301 |
| ISBN-13 | 978-0-12-379030-9 / 9780123790309 |
| Zustand | Neuware |
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