Function and Regulation of Cellular Systems

Professor Dr. Walter Zimmermann ist Vizepräsident des Landgerichts Passau a.D. und Honorarprofessor für Bürgerliches Recht und Zivilprozessrecht an der Universität Regensburg.

to Part I.- A Functional Dynamics Approach to Modelling of Glycolysis.- Temperature-Compensation in Biological Clocks:Models and Experiments.- Metabolic Control Analysis of the ATPase Network in Contracting Muscle:Regulation of Contractile Function and ATP Free Energy Potential.- En Route for Systems Biology: In Silico Pathway Analysis and Metabolite Profiling.- to Part II.- Presynaptic Calcium Dynamics of Neurons in Answer to VariousStimulation Protocols.- Mathematical Modeling of Signaling Cascades: Principles and Future Prospects.- Collective Behavior of Membrane Channels: Electro-physiological Studies on Gap Junctions.- Modelling of Periodic Intercellular Ca2+ Waves.- Travelling Waves as a Mechanism of Pattern Generation in Discrete Cell Lattices.- Design and Operation: Keys to Understanding Biological Systems.- to Part III.- Biopolymer Dynamics.- Micromechanics of Molecular Motors: Experiments and Theory.- The Role of Osteocalcin in the Remodeling of Biomimetic Hydroxyapatite-Collagen Materials for Bone Replacement.- Cell Shape Normalization of Normal and Haploinsufficient NF1-Melanocytes by Micro-Structured Substrate Interaction.- Quantification of Shear Stress-Induced Cell Migration in Endothelial Cultures.- to Part IV.- Constructive and Dynamical Systems Approach to Life.- Coherent Dynamics in Networks of Single Protein Molecules.- Gene Regulatory Networks: A Discrete Model of Dynamics and Topological Evolution.- Evolutionary Reconstruction of Networks.- Modelling Simple Biochemical Networks.- On the Evolution of Information in the Constituents of Regulatory Gene Networks.- to Part V.- Biological Relevance of Tissue Liquidity and Viscoelasticity.- Reinforcement of Cytoskeleton-Matrix Bonds and Tensiotaxis: A Cell-Based Model.- Simulation of Haematopoietic Stem Cell Organisation Using a Single Cell Based Model Approach.- Pattern Formation in an Interacting Cell System: Rippling in Myxobacterial Aggregates.- to Part VI.- Molecular and Cellular Analysis of De Novo Pattern Formation in Hydra.- The Small Freshwater Polyp Hydra as a Model for Axis Formationin Higher Organisms.- Cell Migration, Cell Fate and Pattern Formation During Head Development in Lungfishes and Amphibians.- Cell-Based Modelling of Tissues.- to Part VII.- Cell-Based Models of Avascular Tumor Growth.- Solid Tumor Invasion: The Importance of Cell Adhesion.- Interrelationship of Tumor and Immune System.- Nonlinear Dynamics and Statistical Physics of Models for the Immune System.- Stochastic Model of Influenza Virus Fusion.- Spatio-Temporal Aspects of a Dynamical Disease: Waves of Spreading Depression.- List of contributors.- Color Plates.