Weighted Network Analysis

Applications in Genomics and Systems Biology

(Autor)

Buch | Hardcover
421 Seiten
2011
Springer-Verlag New York Inc.
978-1-4419-8818-8 (ISBN)

Lese- und Medienproben

Weighted Network Analysis - Steve Horvath
213,99 inkl. MwSt
High-throughput measurements of gene expression and genetic marker data facilitate systems biologic and systems genetic data analysis strategies. Gene co-expression networks have been used to study a variety of biological systems, bridging the gap from individual genes to biologically or clinically important emergent phenotypes.

Preface.- Networks and fundamental concepts.- Approximately factorizable networks.- Different type of network concepts.- Adjacency functions and their topological effects.- Correlation and gene co-expression networks.- Geometric interpretation of correlation networks using the singular value decomposition.- Constructing networks from matrices.- Clustering Procedures and module detection.- Evaluating whether a module is preserved in another network.- Association and statistical significance measures.- Structural equation models and directed networks.- Integrated weighted correlation network analysis of mouse liver gene expression data.- Networks based on regression models and prediction methods.- Networks between categorical or discretized numeric variables.- Networks based on the joint probability distribution of random variables.- Index.

Erscheint lt. Verlag 4.5.2011
Zusatzinfo XXIII, 421 p.
Verlagsort New York, NY
Sprache englisch
Maße 155 x 235 mm
Themenwelt Mathematik / Informatik Informatik Theorie / Studium
Informatik Weitere Themen Bioinformatik
Studium 2. Studienabschnitt (Klinik) Humangenetik
Naturwissenschaften Biologie Genetik / Molekularbiologie
ISBN-10 1-4419-8818-1 / 1441988181
ISBN-13 978-1-4419-8818-8 / 9781441988188
Zustand Neuware
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