Understanding Radiation Biology -

Understanding Radiation Biology

From DNA Damage to Cancer and Radiation Risk

Thomas N. Corns (Herausgeber)

Buch | Hardcover
16 Seiten
2019
CRC Press (Verlag)
978-0-367-25515-2 (ISBN)
299,25 inkl. MwSt
This textbook provides a exploration into the action of radiation, taking readers into the cell and discussing the damage and the consequences of radiation exposure to living matter. This book will provide the foundations of radiation biology for undergraduate and graduate students in medical physics, biomedical engineering, and medicine.
This book provides a qualitative and quantitative exploration of the action of radiation on living matter which leads to a complete and coherent interpretation of radiation biology. It takes readers from radiation-induced molecular damage in the nucleus of the cell and links this damage to cellular effects such as cell killing, chromosome aberrations and mutations before exploring organ damage, organism lethality and cancer induction. It also deals with radiological protection concepts and the difficulties of predicting the dose–effect relationship for low-dose and dose rate radiation risk. The book ends with separate chapters dealing with the effects of UV light exposure and risk classification of chemical mutagens, both of which are derived by logical extensions of the radiation model. This book will provide the basic foundations of radiation biology for undergraduate and graduate students in medical physics, biomedical engineering, radiological protection, medicine, radiology and radiography.

Features






Presents a comprehensive insight into radiation action on living matter



Contains important implications for radiological protection and regulations



Provides analytical methods for applications in radiotherapy

Dr. K. H. Chadwick, now retired, worked as a research scientist in the Netherlands before moving to Belgium to manage research contracts on radiation biological effects in the Euratom Radiation Protection Research Programme of the European Commission in Brussels. He also served on the editorial board of the Journal for Radiological Protection for 10 years and is a fellow of the Institute of Physics (FInst P) and the Society for Radiological Protection (FSRP).

PART I: Ionising Radiation Effects. 1. The Molecular Model and DNA Double Strand Breaks. 2. The Molecular Model for Cellular Effects. 3. The Link from Molecular Lesion to Cellular Effects. 4. DNA Double Strand Breaks and Chromosomal Aberrations. 5. The Effect of Dose Rate, Fractionation and Post-Irradiation Repair. 6. Radiation Quality. 7. Radiation-Induced Cancer. 8. Radiation-Induced Lethality. 9 Radiological Protection. PART II: Ultraviolet Light Effects. 10. The Molecular Model for the Cytotoxic Action of UV Light. PART III: Genotoxicology. 11. An Assessment of the Risk of Chemical Mutagens.

Erscheinungsdatum
Zusatzinfo 207 Illustrations, black and white
Verlagsort London
Sprache englisch
Maße 156 x 234 mm
Gewicht 521 g
Themenwelt Geisteswissenschaften Sprach- / Literaturwissenschaft Anglistik / Amerikanistik
Geisteswissenschaften Sprach- / Literaturwissenschaft Literaturwissenschaft
Medizin / Pharmazie Medizinische Fachgebiete Onkologie
Medizinische Fachgebiete Radiologie / Bildgebende Verfahren Radiologie
Naturwissenschaften Biologie
Naturwissenschaften Physik / Astronomie Angewandte Physik
ISBN-10 0-367-25515-4 / 0367255154
ISBN-13 978-0-367-25515-2 / 9780367255152
Zustand Neuware
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