Mechanical Circulatory and Respiratory Support

Shaun D. Gregory has Bachelor, Masters and PhD degrees in medical engineering and has completed research in some of the world’s leading cardiovascular device research institutes. He has multiple research publications, grants, patents and awards. Shaun is a research fellow in the Griffith University School of Engineering and directs the Innovative Cardiovascular Engineering and Technology Laboratory, a world-class research facility with a team of biomedical, mechanical and electrical engineers who work alongside clinicians to develop devices to support the heart and lungs. Jutta Arens is a Mechanical Engineer and Professor in Engineering Organ Support Technologies at the University of Twente in the Netherlands since 2019. She completed her PhD and Habilitation at RWTH Aachen University, Germany, where she worked on the development and research of circulatory and respiratory support devices from 2005 – 2019 at the Institute of Applied Medical Engineering in the Department of Cardiovascular Engineering. She is member of the Board of Trustees of the American Society of Artificial Organs, the Scientific Advisory Board of the German Federal Institute of Drugs and Medical Devices (BfArM), and the International Standardization Organization´s ISO/TC 150/SC 2 working group 4 – Extracorporeal Circuits. Andrew Stephens is a biomedical engineer specialising in medical sensors and smart devices. Andrew completed his PhD at Griffith University developing new ways to control artificial heart devices. Andrew is a research fellow at Monash University and Deputy Director of the Cardio-Respiratory Engineering Laboratory. Andrew’s current research focus is on smart devices and artificial intelligence for emergency medicine. Dr. Heinsar is an emerging clinician-researcher at the University of Queensland with a focus on mechanical circulatory support and a special interest in extracorporeal membrane oxygenation. He is a research fellow at the Critical Care Research Group, a global leader in translational critical care research. His contributions to ECMO research are internationally recognised as he is the 1st dual-recipient of the prestigious European Extracorporeal Life Support Organization Young Investigator Award. John Fraser is the Founder and Director of the Critical Care Research Group, Director of the ICU at St Andrew’s War Memorial Hospital, President of AP-ELSO and a Professor of Medicine at the University of Queensland. His research spans across several disciplines including medicine, biomedical science, engineering and more. John’s work has changed clinical practice on a global scale on several occasions, while his passion for innovation continues to change the scientific fields that he works in. Dr. Fraser has won numerous prizes and fellowships for his research, and contributed to the education of countless clinicians, scientists and engineers.

Section 1 – Heart Failure and Non-device Treatment
1. The Descent into Heart and Lung Failure
2. Heart and Lung Transplantation
3. Ex-vivo Organ Support

Section 2 – Types of Cardio-Respiratory Devices
4. Ventricular Assist Devices: Volume Displacement Pumps
5. Ventricular Assist Devices: Rotary Blood Pumps
6. Total Artificial Hearts
7. Devices for HFpEF
8. Extracorporeal Membrane Oxygenation
9. Pediatric Devices

Section 3 – Pump Design
10. Hydraulic Design
11. Motor design and Impeller Suspension
12. Design for Manufacture
13. Pulsatile vs Continuous Flow
14. Preclinical Evaluation

Section 4 - Implantation and Medical Management
15. Optimising the Patient and Timing the Introduction of MCS
16. Surgical Implantation
17. Complications and Adverse Events
18. Medical Management of the Supported Patient

Section 5 - Physiological Interaction between the Device and Patient
19. Cannula Design
20. Blood-Device Interaction
21. Physiological Control
22. Systems for Power and Data Transfer
23. Oxygenator Design
24. Wearable Systems

Section 6 – Route to Market (And Staying There!)
25. Route to Market
26. Clinical Trials
27. Cost Effectiveness
28. Regulatory Approvals
29. Reimbursement

Section 7 – Summaries
30. The Past, Present and Future