The Toxicology and Biochemistry of Insecticides
Crc Press Inc (Verlag)
978-1-4200-5975-5 (ISBN)
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The first book in two decades to address this multi-faceted field, The Toxicology and Biochemistry of Insecticides provides the most up-to-date information on insecticide classification, formulation, mode of action, resistance, metabolism, environmental fate, and regulatory legislation. The book draws on the author’s groundbreaking research in insect detoxification. It discusses mechanisms at the molecular level such as specific enzymes that contribute to insecticide resistance, the modification of which can change insecticide susceptibility and influence host plant selections in phytophagous insects.
Beginning with a general introduction, eleven chapters integrate classical toxicology with physiology, biochemistry, and molecular biology to present a comprehensive look at the field. The book discusses the demand and formulation of pesticides and describes each type from dusts and powders to baits and aerosols. It classifies insecticides by target, chemical compound, and mechanism; evaluates toxicity testing procedures; explains pesticide uptake, mode of action, and metabolism; and explores species differences, resistance, and interactions. It also considers pesticides in the environment and federal and state regulatory legislation and enforcement.
A long-awaited, state-of-the-science review on insect toxicology, this indispensable book brings you up-to-date on the many aspects and implications of pesticide use and provides the necessary background and platform from which to conduct future research.
The Need for Pesticides and Their Pattern of Use
The Need for Pesticides
Pattern of Use
Pesticide Economics
The Formulation of Pesticides
Types of Formulation
The NonPesticidal Ingredients of Formulations
Pesticide Application Equipment
Pesticide Laws and Regulations
The Federal Insecticide, Fungicide, and Rodenticide Act
The Federal Food, Drug, and Cosmetic Act
The Food Quality Protection Act
State Laws
Enforcement
The Classification of Insecticides
Classification of Insecticides
Evaluation of Toxicity
Testing Procedures
Tests with Insects
Tests with Higher Animals
Probit Analysis
Source of Variability in Dose–Response Tests
The Use of Log Dosage-Probit (LDP) Lines
Appendix 5.1: An example of probit analysis using the SAS system
The Uptake of Insecticides
Penetration of Insecticides Through the Insect Cuticle
Entry via the Mouth
Uptake via the Spiracles
The Mode of Action of Insecticides
Insecticides Affecting Voltage-Gated Sodium Channels
Insecticides Affecting Calcium Channels
Insecticides Inhibiting Acetylcholinesterase
Insecticides Interfering with GABA-gated Chloride Channels
Insecticides that Bind to Nicotinic Acetylcholine Receptor
Insecticides Affecting Octopamine Receptors
Insecticides Interfering with Respiration
Insecticides Acting as Alimentary Toxins
Insecticides Affecting Chitin Biosynthesis or Cuticle Sclerotization
Insecticides Acting as Juvenile Hormone Mimics
Insecticides Acting as Ecdysone Agonists, or Blocking Molting Hormone Activity
Insecticides Abrading or Disrupting Insect Cuticle
The Mode of Action of Acaricides
Principles of Pesticide Metabolism
Phase I Reactions
Phase II Reactions
Metabolic Pathways of Selected Insecticides
Species Differences and Other Phenomena Associated with the Metabolism of Xenobiotics
Species Differences in Detoxification Enzyme Activity
Effect of Age and Sex on Enzyme Activity
The Specificity of Detoxification Enzymes
Selective Toxicity
Synergism and Antagonism
Enzyme Induction
Insecticide Resistance
Insecticide Resistance
The Genetics of Resistance
Mechanisms of Resistance
Interaction Phenomena
Rate of Development of Resistance
Management of Resistance
Pesticides in the Environment
Persistence of Pesticides in Soil
Photodegradation of Pesticides
Pesticides and the Food Chain
Sublethal Effects of Pesticides on Wildlife
| Erscheint lt. Verlag | 8.4.2008 |
|---|---|
| Zusatzinfo | 7 equations; 1 Halftones, black and white; 47 Tables, black and white; 142 Illustrations, black and white |
| Verlagsort | Bosa Roca |
| Sprache | englisch |
| Maße | 178 x 254 mm |
| Gewicht | 680 g |
| Themenwelt | Naturwissenschaften ► Chemie ► Technische Chemie |
| Technik | |
| Weitere Fachgebiete ► Land- / Forstwirtschaft / Fischerei | |
| ISBN-10 | 1-4200-5975-0 / 1420059750 |
| ISBN-13 | 978-1-4200-5975-5 / 9781420059755 |
| Zustand | Neuware |
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