Fungal Genetics

Bos/, Cees

Part 1 Genetic principles: biology of fungi; mutation; meiotic recombination; somatic recombination; molecular genetic analysis; the meiotic system of fungi; extrachromosomal and transposable genetic elements; genetic transformation and vector developments in filamentous fungi; mapping and breeding strategies. Part 2 Case studies of genetic analyses: mitochondrial genetics of saccharomyces cerevisiae - the way from genetic crosses to transposable elements; construction of a physical map of the candida albicans genome; use of heterologous gene as marker for genetic analysis in aspergillus niger; mutation in neurospora crassa - from x-rays to RIP; genetic analysis and mapping of avirulence genes in magnaporte grisea; genetic analysis of senescence in podospora anerina; horizontal transmission in fungal populations; genetic analysis in the imperfect fungus cladosporium fulvum - the development of a map-based strategy for cloning of genes involved in pathogenicity; production and analysis of meiotic mutants in corpinus cinereus; a case study in fungal development and genetics - schizophyllum commune; genetics of phycomyces; genetic analysis of the oomycetous fungus, phytophthora infestans.