Ethnomedicine and Drug Discovery -

Ethnomedicine and Drug Discovery (eBook)

M.M. Iwu, J. Wootton (Herausgeber)

eBook Download: PDF
2002 | 1. Auflage
344 Seiten
Elsevier Science (Verlag)
978-0-08-053125-0 (ISBN)
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224,66 inkl. MwSt
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The emergence of new infectious, chronic and drug resistant diseases have prompted scientists to look towards medicinal plants as agents for treatment and prevention. This book provides an interphase between ethnomedical and ethnobotanical approaches to new drug discovery and advances in biotechnology and molecular science that has made it increasingly feasible to transform traditional medicines into modern drugs. These novel approaches also raise new issues and the volume explores economic, ethical and policy considerations of drug development based on indigenous knowledge or traditional medicine.


This work also features standardization and development of phytomedicines for major therapeutic indications, including emerging infectious diseases affecting developing and developed countries.


The publication provides state-of-the-art information on the most innovative science, the research, the industry, the market, and the future of ethnomedicine and drug discovery.


Approx.344 pages

Front Cover 1
Ethnomedicine and Drug Discovery 4
Copyright Page 5
Contents 6
Introduction: therapeutic agents from ethnomedicine 16
Chapter 1. Drugs from nature: past achievements, future prospects 38
Chapter 2. Natural products for high-throughput screening 54
Chapter 3. Medical ethnobotanical research as a method to identify bioactive plants to treat infectious diseases 60
Chapter 4. Development of HerbMed®: an interactive, evidence-based herbal database 70
Chapter 5. Natural products: a continuing source of inspiration for the medicinal chemist 76
Chapter 6. Integrating African ethnomedicine into primary healthcare: a framework for South-eastern Nigeria 86
Chapter 7. Current initiatives in the protection of indigenous and local community knowledge: problems, concepts and lessons for the future 96
Chapter 8. Bioprospecting: using Africa's genetic resources as a new basis for economic development and regional cooperation 118
Chapter 9. Balancing conservation with utilization: restoring populations of commercially valuable medicinal herbs in forests and agroforests 132
Chapter 10. Ethnomedicine of the Cherokee: historical and current applications 140
Chapter 11. Traditional medicines and the new paradigm of psychotropic drug action 148
Chapter 12. Drug discovery through ethnobotany in Nigeria: some results 160
Chapter 13. Plants, products and people: Southern African perspectives 170
Chapter 14. Development of antimalarial agents and drugs for parasitic infections based on leads from traditional medicine: the Walter Reed experience 178
Chapter 15. Health foods in anti-aging therapy: reducers of physiological decline and degenerative diseases 188
Chapter 16. Indigenous peoples and local communities embodying traditional lifestyles: definitions under Article 8(j) of the Convention on Biological Diversity 196
Chapter 17. Garcinia kola: a new look at an old adaptogenic agent 206
Chapter 18. Linking intellectual property rights with traditional medicine 216
Chapter 19. The use of conservation trust funds for sharing financial benefits in bioprospecting projects 226
Chapter 20. The regulation of botanicals as drugs and dietary supplements in Europe 256
Chapter 21. Regulation of herbal medicines in Nigeria: the role of the National Agency for Food and Drug Administration and Control (NAFDAC) 264
Chapter 22. Considerations in the development of public standards for botanicals their dosage forms 274
Chapter 23. The Belize Ethnobotany Project: safeguarding medicinal plants and traditional knowledge in Belize 282
Chapter 24. Ethnobotanical research into the 21st century 298
Chapter 25. Ethnobotanical approach to pharmaceutical drug discovery: strengths and limitations 324
Contributors 336
Subject Index 340
Corrigendum 346

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