Amyothropic Lateral Sclerosis

This revised and rewritten new edition is specifically addressed to the needs of patients and families living with the reality of ALS.

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Since publication of the first edition of this book, the understanding and treatment of ALS have changed dramatically. The many puzzles of this disease are being steadily solved. One cause of familial ALS has been identified, and the mechanisms of motor neuron cell death are much better understood. The FDA has approved riluzole, the first drug available for the treatment of ALS. Additional drugs are being tested and others are on the horizon. This comprehensive guide covers every aspect of the management of ALS. Beginning with discussions of clinical features of the disease, diagnosis, and an overview of symptom management. Major sections deal with medical and rehabilitative management, living with ALS, managing advanced disease, end-of-life issues, and resources that can provide support and assistance. Regardless of their views about long-range events, everyone dealing with the reality of ALS wants to know what to do now.
Issues that they have or will need to deal with include: * whether to participate in therapeutic trials * the role of rehabilitation treatments * the use of riluzole (Rilutek), as well as new experimental preparations and drugs that have been approved for some other disease and are being used in ALS