Bioanalytical Chemistry

Susan R. Mikkelsen, PhD, is a professor in the Department of Chemistry at the University of Waterloo, Ontario, Canada. Eduardo Cortón, PhD, is an adjunct professor in the Department of Biological Chemistry at the University of Buenos Aires, Argentina. He is also an investigator for the National Council of Scientific and Technical Research (CONICET) in Argentina.

Preface.
Acknowledgments.


1. Spectroscopic Methods for Matrix Characterization.


2. Enzymes.


3. Quantitation of Enzymes and Their Substrates.


4. Immobilized Enzymes.


5. Antibodies.


6. Quantitative Immunoassays with Labels.


7. Biosensors.


8. Directed Evolution for the Design of Macromolecular Bioassay Reagents.


9. Principles of Electrophoresis.


10. Applications of Zone Electrophoresis.


11. Isoelectric Focusing.


12. Capillary Electrophoresis.


13. Centrifugation Methods.


14. Chromatography of Biomolecules.


15. Mass Spectrometry of Biomolecules.


16. Validation of New Bioanalytical Methods.


Suggested References.


References.


Answers to Problems.


Index.