Myosins

Lynne Coluccio, PhD, began her career at Boston University as a Principal Scientist at the Boston Biomedical Research Institute (BBRI) in 1996. After the institute was closed in 2013, she became a Research Associate in the Department of Physiology & Biophysics at the Boston University School of Medicine and has remained since then. While at the BBRI, she played a variety of roles on the committee including as a chair of the Faculty Search Committee and as a member of the Public Relations Committee. Throughout her she career she has mentored dozens of students who have gone into academia, medicine, teaching, and music.

Introduction.- Myosin Structure.- Cargo Binding by Unconventional Myosins.- Cryo-EM of Actin-Myosin Structures.- Small Molecule Effectors of Myosin Function.- Single-Molecule Biophysical Techniques to Study Actomyosin Force Transduction.- High-Speed Atomic Force Microscopy to Study Myosin Motility.- How Myosin 5 Walks Deduced from Single-Molecule Biophysical Approaches.- How Actin Tracks Affect Myosin Motors.- Myosins in the Nucleus.- Myosins in Cytokinesis.- Myosins and Disease.- Myosins and Hearing.- The Actomyosin Systems in Apicomplexa.- Approaches to Identify and Characterise MYO6-Cargo Interactions.- Class IX Myosins: Motorized RhoGAP Signaling Molecules.- Myosin X.- Myosin XVI.- Myosin XVIII.- Myosin XIX