Peptide Nucleic Acids

Fmoc-based Assembly of PNA Oligomers: Manual and Microwave-assisted Automated Synthesis.- A Robust Method for Preparing Optically Pure MiniPEG-Containing Gamma PNA Monomers.- Synthesis of Pyrrolidinyl PNA and Its Site-specific Labeling at Internal Positions by Click Chemistry.- Synthesis of PNA-peptide Conjugates as Functional SNARE Protein Mimetics.- Lipid-modified Peptide Nucleic Acids – Synthesis and Application to Programmable Liposome Fusion.- Facile Preparation of PNA-Peptide Conjugates with a Polar Maleimido-thioether Linkage.- PNA-Encoded Synthesis (PES) and DNA Display of Small Molecule Libraries.- Transcription Inhibition by PNA-induced R-loops.- Nucleobase-Modified Triplex-Forming Peptide Nucleic Acids for Sequence-Specific Recognition of Double-Stranded RNA.- In Vitro Cellular Delivery of Peptide Nucleic Acid (PNA).- Reactive Quantum Dot-based FRET Systems for Target-catalyzed Detection of RNA.- Peptide Nucleic Acids for MicroRNAs Targeting.- Detection of Microorganismsby Fluorescence in situ Hybridization using Peptide Nucleic Acid.- PNA Antisense Targeting in Bacteria. Determination of Antibacterial Activity (MIC) of PNA-peptide Conjugates.- In vivo Administration of Splice Switching PNAs using the mdx Mouse as a Model System.- Near Infrared in vivo Whole Body Fluorescence Imaging of PNA.- Poly(lactic-co-glycolic acid) Nanoparticle Delivery of Peptide Nucleic Acids In Vivo.- Preparation of Conjugates for Affibody-based PNA-mediated Pretargeting.