Tumor Profiling
Humana Press Inc. (Verlag)
978-1-4939-9002-3 (ISBN)
Authoritative and cutting-edge, Tumor Profiling: Methods and Protocols aims to be a useful resource for learning about technical details, applications, and strengths and limitations of the latest technologies as applied to this increasingly important field.
Amplicon-based Targeted Next Generation Sequencing of Formalin Fixed Paraffin Embedded Tissue.- Library preparation using FFPE-derived Tumor DNA for High Throughput Hybridization-based Targeted or Exome Sequencing.- Bioinformatics Basics for High Throughput Hybridization-based Targeted DNA Sequencing From FFPE-Derived Tumor Specimens: From Reads to Variants.- Annotation of Variant Data from High Throughput DNA Sequencing from Tumor Specimens: Filtering Strategies to Identify Driver Mutations.- Biological Interpretation of Complex Genomic Data.- Clinical Validation of Targeted Solid Tumor Profiling.- Whole Genome Single Nucleotide Polymorphism Microarray for Copy Number and Loss of Heterozygosity Analysis in Tumors.- Genome-Wide Copy Number Variation Detection using NGS: Data Analysis and Interpretation.- Overview of Fusion Detection Strategies Using Next Generation Sequencing.- Clinical Application of Fusion Gene Detection Using Next-generation Sequencing and the NanoString Technology.- Pipeline for Integrated Microarray Expression Normalization Toolkit (PIMENTo) for Tumor Microarray Profiling Experiment.- Molecular Profiling of RNA Tumors using High Throughput RNA Sequencing: Overview of Library Preparation Methods.- Molecular Profiling of RNA Tumors using High Throughput RNA Sequencing: From Raw Data to Systems Level Analyses.- Methylation Analysis using Microarrays: Analysis and Interpretation.- High-Throughput Targeted Repeat Element Bisulfite Sequencing (HT-TREBS).- A Pipeline for ctDNA Detection Following Primary Tumor Profiling Using A Cancer-related Gene Sequencing Panel.- Single-cell Analysis of Circulating Tumor Cells.
Erscheinungsdatum | 05.02.2019 |
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Reihe/Serie | Methods in Molecular Biology ; 1908 |
Zusatzinfo | 57 Illustrations, color; 15 Illustrations, black and white; XI, 268 p. 72 illus., 57 illus. in color. |
Verlagsort | Totowa, NJ |
Sprache | englisch |
Maße | 178 x 254 mm |
Themenwelt | Medizin / Pharmazie ► Medizinische Fachgebiete ► Onkologie |
Medizin / Pharmazie ► Studium | |
Naturwissenschaften ► Biologie ► Genetik / Molekularbiologie | |
Schlagworte | genomic alterations • Heterogeneity • NGS • qPCR • Strs |
ISBN-10 | 1-4939-9002-0 / 1493990020 |
ISBN-13 | 978-1-4939-9002-3 / 9781493990023 |
Zustand | Neuware |
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