Vertebrate Development

Dr. Francisco Pelegri is currently a Professor in the Laboratory of Genetics at the University of Wisconsin-Madison. He received his PhD from the Massachusetts Institute of Technology and his postdoctoral position was at the Max Planck Institute for Developmental Biology, Tübingen, Germany. His research focus is understanding at the cellular and molecular level processes involved in early zebrafish development, specifically but not exclusively the functional diversification of cell types. Dr. Michael V. Danilchik is a Professor in the Department of Integrative Biosciences at Oregon Health & Science University. He received his PhD from the University of Washington and did his postdoctoral training at the University of California, Berkeley. His research interest is in cellular mechanisms of pregastrular morphogenesis, particularly cytoskeletal and membrane dynamics during cleavage-stage cytokinesis, and long-range cell-cell signaling modalities involving filopodia and extracellular vesicles. Dr. Ann E. Sutherland is an Associate Professor, Cell Biology at the School of Medicine at University of Virginia. She earned her PhD at the University of California San Francisco. Her laboratory's research focuses primarily on the cellular mechanisms of implantation and gastrulation in the mouse embryo and, in particular, the regulation of motility in the trophoblast cells of the implanting mouse blastocyst, and the cell behaviors leading to axial elongation in the mid-gestation embryo.

Preface.- 1. Egg Activation at Fertilization.- 2. Controlling the Messenger: Regulated Translation of Maternal mRNAs in Xenopus laevis Development.- 3. Regulation of Cell Division.- 4. Vertebrate Embryonic Cleavage Pattern Determination.- 5. Localization in Oogenesis of Maternal Regulators of Embryonic Development.- 6. Vertebrate Axial Patterning: from Egg to Asymmetry.- 7. Establishment of the Vertebrate Germ Layers.- 8. Mechanisms of Vertebrate Germ Cell Determination.- 9. Cell Cycle Remodeling and Zygotic Gene Activation at the Midblastula Transition.- 10. Clearance of Parental Products.- Index.