Nanotechnology and Regenerative Engineering

Cato T. Laurencin, Lakshmi S. Nair

SECTION I Importance of Scaffolds in Tissue Regeneration. Tissue Engineering: The Therapeutic Strategy of the Twenty-First Century . From Microenvironment to Nanoenvironment: Ultrastructure and Function of . Extracellular Matrix. Functions and Requirements of Synthetic Scaffolds in Tissue Engineering. Microfabrication Techniques in Scaffold Development. SECTION II Effect of Nanostructures on Cellular Responses and Tissue Regeneration. Cell Response to Nanoscale Features and Its Implications in Tissue Regeneration: An Orthopedic Perspective. Surface Modification of Biomaterials at the Nanoscale: Biomimetic Scaffolds for Tissue Engineering Applications. SECTION III Promising Nanofabrication Techniques for Scaffolds to Support Tissue Regeneration. Electrospun Polymeric Nanofiber Scaffolds for Tissue Regeneration. Structure and Mechanical Properties of Electrospun Nanofibers and Nanocomposites. Electrospinning Techniques to Control Deposition and Structural Alignment of Nanofibrous Scaffolds for Cellular Orientation and Cytoskeletal Reorganization. Nanolithographic Techniques in Tissue Engineering. Designer Self-Assembling Peptide Scaffolds for Tissue Engineering and Regenerative Medicine. SECTION IV Applications of Nanostructured Scaffolds in Biology and Medicine. Nanotechnologies to Promote Skin Tissue Regeneration . Nanotechnologies for Neural Tissue Engineering . Nanotechnologies for Cardiovascular Tissue Engineering. Nanostructures for Musculoskeletal Tissue Engineering . SECTION V Regulatory Perspectives on Nanostructured Materials. Regulatory Process of Nanostructured Tissue Engineered Products. Index.