Organic Synthesis – A Toolbox and Workbook
Blackwell Verlag GmbH
978-3-527-34239-6 (ISBN)
The text cleverly combines a compact toolbox section with a problem section, the former including short remarks, discussions of reaction mechanisms and a concise overview of the most important modern synthetic methods. The problem section then presents examples of recent literature in natural product total synthesis with synthetic schemes to be completed by students, along with helpful hints and the complete solutions for effective self-monitoring. Instructional mechanisms and key intermediates are discussed, along with the choice of reagents and retrosynthetic considerations, in line with the didactic approach, while cross-references to related synthetic problems and methods are also given. The bonus material includes ambitious, but highly educational reactions.
Prepares students to tackle the challenging topics of retrosynthesis and proper organic reaction mechanisms.
Jürgen Seibel is Professor at the University of Würzburg. He performed his PhD thesis under the guidance of Professor Dr. Dr. h.c. Lutz F. Tietze. He moved for a Postdoc to the University of Oxford in the Dyson Perrins Laboratory (Department of Organic Chemistry) and back in Germany he started his independent research at the University of Braunschweig. After his habilitation he moved to Helmholtz Centre for Infection Research (HZI) and became professor at the University of Würzburg. His present research interests are focused on Bioorganic Chemistry and Chemical Biology including the development of chemical and enzymatic syntheses, biocatalysis, protein engineering, drug delivery and glycosciences. He was awarded with the Jochen-Block prize by the Dechema (Society for Chemical Engineering and Biotechnology) and received the DuPont Young Professor award. Julian Görl and Michael Kraus are PhD students in the the Seibel group.
TOOLBOX
Protecting Groups
Oxidation Reactions (DMP, Swern, DCC, TPAP)
Reduction Reactions
Carbon Acid Activation and C=O Substitution
Essentials of C=O Chemistry
Transition Metal Catalysis
Stereoselective Carbonyl Chemistry
Addition to C=C bonds
Introduction/Formation of C=C Bonds
Introduction/Formation of C=C (Seyferth, Corey-Fuchs)
Pericyclic Reactions
Ene Reactions
Defunctionalisation Reactions
Rearrangement Reactions
Introduction of Hetero-Atoms
Multi-Component Reactions (Ugi, Strecker, Petasis)
PROBLEM SECTION
Selected Instructive Examples in Total Synthesis
| Erscheinungsdatum | 15.08.2019 |
|---|---|
| Verlagsort | Berlin |
| Sprache | englisch |
| Maße | 170 x 244 mm |
| Themenwelt | Naturwissenschaften ► Chemie ► Organische Chemie |
| ISBN-10 | 3-527-34239-7 / 3527342397 |
| ISBN-13 | 978-3-527-34239-6 / 9783527342396 |
| Zustand | Neuware |
| Haben Sie eine Frage zum Produkt? |
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