Müller Cells in the Healthy and Diseased Retina

Andreas Reichenbach, Andreas Bringmann (Autoren)

Buch | Softcover

417 Seiten

2014 | 2010 ed.
Springer-Verlag New York Inc.
978-1-4899-8502-6 (ISBN)

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Müller cells may be used in the future for novel therapeutic strategies to protect neurons against apoptosis (for example, somatic gene therapy), or to differentiate retinal neurons from Müller/stem cells. Meanwhile, a proper understanding of the gliotic responses of Müller cells in the diseased retina, and of their protective vs. detrimental effects, is essential for the development of efficient therapeutic strategies that use and stimulate the neuron-supportive/-protective - and prevent the destructive - mechanisms of gliosis.

Introduction.- Basic properties of Müller cells.- Müller cell gliosis.- Müller cells in the healthy retina.- Retinal Development.- Müller cells as 'light cables'.- Soft Müller cells as shock absorbers and axon paths.- 'Metabolic symbiosis'.- Neurotransmitter recycling.- Retinal K+ homeostasis.- Retinal water homeostasis.- Other interactions.- Müller cells in the diseased retina.- Retinal detachment.- Diabetic retinopathy.- Macular edema.- Proliferative retinopathies.- Ischemia-reperfusion.- Hepatic retinopathy.- Retinoschisis.- Retinitis pigmentosa and support of neuronal survival.- Future directions.- Index.

Erscheint lt. Verlag	30.11.2014
Zusatzinfo	XIV, 417 p.
Verlagsort	New York
Sprache	englisch
Maße	155 x 235 mm
Themenwelt	Medizin / Pharmazie ► Medizinische Fachgebiete ► Augenheilkunde
	Medizin / Pharmazie ► Medizinische Fachgebiete ► Neurologie
	Medizin / Pharmazie ► Studium
	Naturwissenschaften ► Biologie ► Humanbiologie
	Naturwissenschaften ► Biologie ► Zellbiologie
	Naturwissenschaften ► Biologie ► Zoologie
ISBN-10	1-4899-8502-6 / 1489985026
ISBN-13	978-1-4899-8502-6 / 9781489985026
Zustand	Neuware