The Herpesviruses

1 Epidemiology of Herpes Simplex Viruses.- I. Introduction.- II. Historical Background.- III. Descriptive Epidemiology.- IV. Recurrent Infection versus Reinfection with HSV.- V. Diseases of Epidemiologic Importance.- VI. HSV Infections and Cervical Carcinoma.- VII. Conclusion.- References.- 2 Individual HSV Transcripts: Characterization of Specific Genes.- I. Introduction.- II. HSV mRNA.- III. RNA Expressed in the Infected Cell.- IV. Detailed Analysis of Specific HSV Transcripts.- V. Specific HSV Genes.- VI. A Typical HSV-1 Transcription Unit.- VII. Generation of HSV Transcript ‘Families’.- References.- 3 Molecular Biology of Pseudorabies Virus.- I. Introduction.- II. Morphology.- III. Stability in the Presence of Physical and Chemical Agents.- IV. Virus Proteins.- V. Virus Genome.- VI. Virus Replication in Cell Culture.- VII. RNA Synthesis in PRV-Infected Cells.- VIII. Protein Synthesis in the Infected Cells.- IX. DNA Synthesis in PRV-Infected Cells.- X. Origins of DNA Replication.- XI. Mode of PRV DNA Replication.- XII. Maintenance of Sequence Identity of the Inverted Repeats.- XIII. Isomerization of the Virus Genome.- XIV. Process of Virion Assembly.- XV. Organization of the Genome of PRV.- XVI. Cellular Macromolecular Synthesis in the Infected Cells.- XVII. Sequence Homology between the Genomes of PRV and HSV.- XVIII. Aujeszky’s Disease.- References.- 4 Herpes Simplex Virus Latency.- I. Introduction.- II. The Site of Latent Infection.- III. Establishment of Latent Infection in Ganglia.- IV. Reactivation of the Latent Infection and the Production of Recurrent Disease.- References.- 5 Herpes Simplex Viruses and Their Roles in Human Cancer.- I. Introduction.- II. Definition of Risk.- III. Viral Genetic Information in Cancer Cells.- IV. Comments.- References.- 6Transforming Potential of Herpes Simplex Viruses and Human Cytomegalovirus.- I. Introduction.- II. Transforming Potential of HSV.- III. Transforming Potential of HCMV.- IV. Conclusion.- References.- 7 Glycoproteins Specified by Herpes Simplex Virus.- I. Introduction.- II. The HSV Glycoproteins and Their Structural Genes.- III. Synthesis and Processing of the Glycoproteins.- IV. Activities and Roles of the Glycoproteins.- V. Appendix.- References.- 8 Processing of the Oligosaccharide Chains of Herpes Simplex Virus Type 1 Glycoproteins.- I. Introduction.- II. HSV-1 Glycoproteins.- III. Biosynthesis and Characterization of the Oligosaccharide Chains of HSV-1 Glycoproteins.- IV. Relationship between Glyean Structure and Expression of HSV-1 Functions.- References.- 9 Glycoproteins Specified by Human Cytomegalovirus.- I. Introduction.- II. CMV Glycoproteins f.- III. Characterization of CMV Glycoproteins with Monoclonal Antibodies.- IV. Mapping CMV Genes.- V. Synthesis and Processing of CMV gA.- References.