Vesicle Trafficking in Cancer

Preface.- Clathrin Mediated Endocytosis.- Intimate And Facultative? Regulation Of Clathrin-Mediated Endocytosis By The Actin Cytoskeleton.- Oncogenic Signaling From The Plasma Membrane.- Endocytosis In The Spatial Control Of Polarized Cell Functions.- Aberrant Vesicular Trafficking Contributes To Altered Polarity And Metabolism In Cancer.- Endocytosis And The Regulation Of Cell Signaling, Cell Adhesion, And Epithelial To Mesenchymal Transition In Cancer.- Efficient Enhancement Of Signaling Capacity: Signaling Endosomes.- Nuclear Functions And Trafficking Of Receptor Tyrosine Kinases.- Efficient Enhancement Of Signaling Capacity – The Ubiquitin System.-  Molecular Mechanism Of Ubiquitin-Dependent Traffic.- Cbl As A Master Regulator Of Receptor Tyrosine Kinase Trafficking.- Regulation Of Endocytic Trafficking And Signaling By Deubiquitylating Enzymes.- RTKs As Models For Trafficking Regulation - C-Met/HGF-Receptor- C-Met Signalling In Cancer: Location Counts.- Regulation Of Epidermal Growth Factor Receptor Signaling By Endocytosis In Normal And Malignant Cells.- Stress-Driven Endocytosis Of Tyrosine-Phosphorylated EGFR Leads To Tumorigenesis: The Critical Role Of Oxidative Stress.- Internalisation, Endosomal Trafficking And Recycling Of Integrins During Cell Migration And Cancer Invasion.- Antibody-mediated receptor endocytosis: Harnessing the cellular machinery to combat cancer.- Index.